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dexketoprofen trometamol + tramadol hydrochloride — Competitive Intelligence Brief
marketed
NSAID + opioid analgesic combination
COX-1/COX-2 (dexketoprofen); mu-opioid receptor, norepinephrine transporter, serotonin transporter (tramadol)
Pain Management
Small molecule
Live · refreshed every 30 min
Target snapshot
dexketoprofen trometamol + tramadol hydrochloride (dexketoprofen trometamol + tramadol hydrochloride) — Kavaklıdere Umut Hospital. This combination product uses dexketoprofen (a nonsteroidal anti-inflammatory drug) to reduce inflammation and pain, and tramadol (an opioid analgesic) to provide additional pain relief through multiple mechanisms.
Comparator set (2 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| dexketoprofen trometamol + tramadol hydrochloride TARGET | dexketoprofen trometamol + tramadol hydrochloride | Kavaklıdere Umut Hospital | marketed | NSAID + opioid analgesic combination | COX-1/COX-2 (dexketoprofen); mu-opioid receptor, norepinephrine transporter, serotonin transporter (tramadol) | |
| Motrin and narcotic | Motrin and narcotic | Cape Fear Valley Health System | marketed | NSAID + opioid analgesic combination | COX-1/COX-2 (ibuprofen); mu, delta, and kappa opioid receptors (narcotic component) | |
| Naproxen Sodium + Codeine Phosphate | Naproxen Sodium + Codeine Phosphate | ibrahim doğru | marketed | NSAID + opioid analgesic combination | COX-1, COX-2, mu-opioid receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (NSAID + opioid analgesic combination class)
- Cape Fear Valley Health System · 1 drug in this class
- Kavaklıdere Umut Hospital · 1 drug in this class
- ibrahim doğru · 1 drug in this class
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Cite this brief
Drug Landscape (2026). dexketoprofen trometamol + tramadol hydrochloride — Competitive Intelligence Brief. https://druglandscape.com/ci/dexketoprofen-trometamol-tramadol-hydrochloride. Accessed 2026-05-17.
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