Who are Dexchlorpheniramine or Diphenhydramine's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Lastacaft, Xyzal, Elestat, Rupax, Zaditor, Mizollen.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Subscribe to /feed/ci/dexchlorpheniramine-or-diphenhydramine.xml in any RSS reader (Feedly, Inoreader, NewsBlur). Every regulatory action, trial readout, or patent event lands in your feed automatically.

Last reviewed 2026-05-16 · How we verify

Dexchlorpheniramine or Diphenhydramine — Competitive Intelligence Brief

Dexchlorpheniramine or Diphenhydramine (Dexchlorpheniramine or Diphenhydramine) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: H1 receptor antagonist (first-generation antihistamine). Area: Allergy/Immunology.

marketed H1 receptor antagonist (first-generation antihistamine) Histamine H1 receptor Allergy/Immunology Small molecule Live · refreshed every 30 min

Target snapshot

Dexchlorpheniramine or Diphenhydramine (Dexchlorpheniramine or Diphenhydramine) — Sanofi. Blocks histamine H1 receptors to reduce allergic and inflammatory responses.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Dexchlorpheniramine or Diphenhydramine TARGET	Dexchlorpheniramine or Diphenhydramine	Sanofi	marketed	H1 receptor antagonist (first-generation antihistamine)	Histamine H1 receptor
Lastacaft	ALCAFTADINE	AbbVie	marketed	Histamine-1 Receptor Antagonist [EPC]	Histamine H1 receptor	2010-01-01
Xyzal	LEVOCETIRIZINE	Sanofi	marketed	Histamine-1 Receptor Antagonist	Histamine H1 receptor	2007-01-01
Elestat	EPINASTINE	AbbVie	marketed	Adrenergic Receptor Agonist	Histamine H1 receptor	2003-01-01
Rupax	RUPATADINE	Teikoku Seiyaku	marketed	rupatadine	Histamine H1 receptor	2001-01-01
Zaditor	KETOTIFEN		marketed	Histamine-1 Receptor Inhibitor	Histamine H1 receptor	1999-01-01
Mizollen	MIZOLASTINE	Sanofi	marketed	mizolastine	Histamine H1 receptor	1998-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (H1 receptor antagonist (first-generation antihistamine) class)

Federal State Budgetary Scientific Institution, Research Institute of Fundamental and Clinical Immunology · 1 drug in this class
Organon and Co · 1 drug in this class
Sanofi · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Dexchlorpheniramine or Diphenhydramine — Competitive Intelligence Brief. https://druglandscape.com/ci/dexchlorpheniramine-or-diphenhydramine. Accessed 2026-05-16.

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