Last reviewed · How we verify
Desloratadine given orally — Competitive Intelligence Brief
phase 3
H1-receptor antagonist (second-generation/non-sedating antihistamine)
H1 receptor
Allergy/Immunology
Small molecule
Live · refreshed every 30 min
Target snapshot
Desloratadine given orally (Desloratadine given orally) — Hoffmann-La Roche. Desloratadine is a selective H1-receptor antagonist that blocks histamine-mediated allergic responses without significant central nervous system penetration.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Desloratadine given orally TARGET | Desloratadine given orally | Hoffmann-La Roche | phase 3 | H1-receptor antagonist (second-generation/non-sedating antihistamine) | H1 receptor | |
| Lastacaft | ALCAFTADINE | AbbVie | marketed | Histamine-1 Receptor Antagonist [EPC] | Histamine H1 receptor | 2010-01-01 |
| Xyzal | LEVOCETIRIZINE | Sanofi | marketed | Histamine-1 Receptor Antagonist | Histamine H1 receptor | 2007-01-01 |
| Elestat | EPINASTINE | AbbVie | marketed | Adrenergic Receptor Agonist | Histamine H1 receptor | 2003-01-01 |
| Rupax | RUPATADINE | Teikoku Seiyaku | marketed | rupatadine | Histamine H1 receptor | 2001-01-01 |
| Zaditor | KETOTIFEN | marketed | Histamine-1 Receptor Inhibitor | Histamine H1 receptor | 1999-01-01 | |
| Mizollen | MIZOLASTINE | Sanofi | marketed | mizolastine | Histamine H1 receptor | 1998-01-01 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (H1-receptor antagonist (second-generation/non-sedating antihistamine) class)
- ALK-Abelló A/S · 1 drug in this class
- Hoffmann-La Roche · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Desloratadine given orally — Competitive Intelligence Brief. https://druglandscape.com/ci/desloratadine-given-orally. Accessed 2026-05-16.
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