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Desloratadine (Clarinex) — Competitive Intelligence Brief

Desloratadine (Clarinex) (Desloratadine (Clarinex)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Non-sedating H1-receptor antagonist. Area: Immunology / Allergy.

phase 3 Non-sedating H1-receptor antagonist Histamine H1 receptor Immunology / Allergy Small molecule Live · refreshed every 30 min

Target snapshot

Desloratadine (Clarinex) (Desloratadine (Clarinex)) — Organon and Co. Desloratadine is a selective histamine H1-receptor antagonist that blocks histamine-mediated allergic responses without significant central nervous system penetration.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Desloratadine (Clarinex) TARGET Desloratadine (Clarinex) Organon and Co phase 3 Non-sedating H1-receptor antagonist Histamine H1 receptor
Lastacaft ALCAFTADINE AbbVie marketed Histamine-1 Receptor Antagonist [EPC] Histamine H1 receptor 2010-01-01
Xyzal LEVOCETIRIZINE Sanofi marketed Histamine-1 Receptor Antagonist Histamine H1 receptor 2007-01-01
Elestat EPINASTINE AbbVie marketed Adrenergic Receptor Agonist Histamine H1 receptor 2003-01-01
Rupax RUPATADINE Teikoku Seiyaku marketed rupatadine Histamine H1 receptor 2001-01-01
Zaditor KETOTIFEN marketed Histamine-1 Receptor Inhibitor Histamine H1 receptor 1999-01-01
Mizollen MIZOLASTINE Sanofi marketed mizolastine Histamine H1 receptor 1998-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Non-sedating H1-receptor antagonist class)

  1. Organon and Co · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Desloratadine (Clarinex) — Competitive Intelligence Brief. https://druglandscape.com/ci/desloratadine-clarinex. Accessed 2026-05-16.

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