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EXDENSUR — Competitive Intelligence Brief
marketed
IL-5
Other
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Target snapshot
EXDENSUR (DEPEMOKIMAB-ULAA) — GLAXOSMITHKLINE LLC. Depemokimab-ulaa binds to IL-5, blocking its interaction with the IL-5 receptor and reducing eosinophil activity.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| EXDENSUR TARGET | DEPEMOKIMAB-ULAA | GLAXOSMITHKLINE LLC | marketed | IL-5 | ||
| Benralizumab Prefilled Syringe | Benralizumab Prefilled Syringe | Nantes University Hospital | marketed | IL-5 receptor antagonist monoclonal antibody | IL-5 receptor alpha (IL-5Rα) | |
| anti IL5 receptor antibodies | anti IL5 receptor antibodies | Scarlata, Simone, M.D. | marketed | IL-5 receptor antagonist monoclonal antibody | IL-5 receptor (IL-5R) | |
| Fasenra® | Fasenra® | AstraZeneca | marketed | IL-5 receptor antagonist monoclonal antibody | IL-5Rα (interleukin-5 receptor alpha) | |
| Mepolizumab Injection [Nucala] | Mepolizumab Injection [Nucala] | KU Leuven | marketed | IL-5 antagonist monoclonal antibody | IL-5 (Interleukin-5) | |
| Asthma therapies | Asthma therapies | Genentech, Inc. | marketed | Monoclonal antibodies (multiple agents with different targets) | IgE, IL-5, IL-4 receptor alpha (varies by specific agent) | |
| Placebo matching mepolizumab | Placebo matching mepolizumab | GlaxoSmithKline | phase 3 | IL-5 inhibitor | IL-5 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape
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Cite this brief
Drug Landscape (2026). EXDENSUR — Competitive Intelligence Brief. https://druglandscape.com/ci/depemokimab-ulaa. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing