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Deferred aflibercept — Competitive Intelligence Brief
phase 3
VEGF inhibitor / Antiangiogenic agent
VEGF (vascular endothelial growth factor), PlGF (placental growth factor)
Ophthalmology / Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Deferred aflibercept (Deferred aflibercept) — Jaeb Center for Health Research. Aflibercept is a recombinant fusion protein that acts as a soluble decoy receptor for vascular endothelial growth factor (VEGF) and placental growth factor (PlGF), binding and neutralizing these pro-angiogenic factors.
Comparator set (4 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Deferred aflibercept TARGET | Deferred aflibercept | Jaeb Center for Health Research | phase 3 | VEGF inhibitor / Antiangiogenic agent | VEGF (vascular endothelial growth factor), PlGF (placental growth factor) | |
| Ziv aflibercept | Ziv aflibercept | Marashi Eye Clinic | marketed | VEGF inhibitor / Antiangiogenic agent | VEGF-A, VEGF-B, PlGF (Placental Growth Factor) | |
| Prompt aflibercept | Prompt aflibercept | Jaeb Center for Health Research | phase 3 | VEGF inhibitor / Antiangiogenic agent | VEGF (vascular endothelial growth factor), PlGF (placental growth factor) | |
| Eylea HD (aflibercept HD) | Eylea HD (aflibercept HD) | Alvotech Swiss AG | phase 3 | VEGF inhibitor / Antiangiogenic agent | VEGF-A, PlGF (Placental Growth Factor) | |
| Eylea® Solution for intravitreal injection | Eylea® Solution for intravitreal injection | Rophibio, Inc. | phase 3 | VEGF inhibitor / Antiangiogenic agent | VEGF-A, VEGF-B, PlGF (placental growth factor) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (VEGF inhibitor / Antiangiogenic agent class)
- Jaeb Center for Health Research · 2 drugs in this class
- Alvotech Swiss AG · 1 drug in this class
- Marashi Eye Clinic · 1 drug in this class
- Rophibio, Inc. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Deferred aflibercept — Competitive Intelligence Brief. https://druglandscape.com/ci/deferred-aflibercept. Accessed 2026-05-15.
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