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Daivobet® gel — Competitive Intelligence Brief
phase 3
Topical combination therapy (vitamin D analog + corticosteroid)
Vitamin D receptor (VDR); glucocorticoid receptor (GR)
Dermatology
Small molecule
Live · refreshed every 30 min
Target snapshot
Daivobet® gel (Daivobet® gel) — LEO Pharma. Daivobet combines calcipotriene (a vitamin D analog) and betamethasone dipropionate (a corticosteroid) to reduce inflammation and normalize skin cell differentiation in psoriasis.
Comparator set (4 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Daivobet® gel TARGET | Daivobet® gel | LEO Pharma | phase 3 | Topical combination therapy (vitamin D analog + corticosteroid) | Vitamin D receptor (VDR); glucocorticoid receptor (GR) | |
| calcipotriene + clobetasol propionate | calcipotriene + clobetasol propionate | Leon Kircik, M.D. | marketed | Topical combination therapy (vitamin D analog + corticosteroid) | Vitamin D receptor (VDR) and glucocorticoid receptor (GR) | |
| Calcipotriene and betamethasone dipropionate ointment | Calcipotriene and betamethasone dipropionate ointment | Galderma R&D | marketed | Topical combination therapy (vitamin D analog + corticosteroid) | Vitamin D receptor (VDR) and glucocorticoid receptor (GR) | |
| LEO 90105 = calcipotriol + betamethasone dipropionate | LEO 90105 = calcipotriol + betamethasone dipropionate | LEO Pharma | phase 3 | Topical combination therapy (vitamin D analog + corticosteroid) | Vitamin D receptor (VDR); glucocorticoid receptor (GR) | |
| Calcipotriene/betamethasone gel and ointment | Calcipotriene/betamethasone gel and ointment | LEO Pharma | phase 3 | Topical combination therapy (vitamin D analog + corticosteroid) | Vitamin D receptor (VDR); glucocorticoid receptor (GR) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Topical combination therapy (vitamin D analog + corticosteroid) class)
- LEO Pharma · 3 drugs in this class
- Galderma R&D · 1 drug in this class
- Leon Kircik, M.D. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Daivobet® gel — Competitive Intelligence Brief. https://druglandscape.com/ci/daivobet-gel. Accessed 2026-06-10.
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