Last reviewed · How we verify
Cosmegen — Competitive Intelligence Brief
marketed
Actinomycin [EPC]
DNA
Oncology
Recombinant protein
Live · refreshed every 30 min
Target snapshot
Cosmegen (DACTINOMYCIN) — Recordati. Dactinomycin binds DNA and inhibits RNA synthesis, demonstrating cytotoxic activity in cancer models.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Cosmegen TARGET | DACTINOMYCIN | Recordati | marketed | Actinomycin [EPC] | DNA | 1964-01-01 |
| CEDAZURIDINE | CEDAZURIDINE | marketed | Nucleoside Metabolic Inhibitor [EPC] | DNA methyltransferase | 2020-01-01 | |
| Dacogen | decitabine | Sun Pharma | marketed | Nucleoside Metabolic Inhibitor [EPC] | DNA (cytosine-5)-methyltransferase 1 | 2006-01-01 |
| Vidaza | azacitidine | Bristol-Myers Squibb | marketed | Nucleoside Metabolic Inhibitor [EPC] | DNA (cytosine-5)-methyltransferase 1 | 2004-01-01 |
| Zymar | GATIFLOXACIN | Allergan | marketed | DNA gyrase, DNA gyrase, DNA gyrase subunit A | 2003-01-01 | |
| Hepsera | ADEFOVIR DIPIVOXIL | Gilead Sciences | marketed | Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor | DNA polymerase subunit gamma-1 | 2002-01-01 |
| Eloxatin | Oxaliplatin | Yakult Honsha | marketed | Platinum-based chemotherapy agent | DNA | 2002-01-01 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
- — Vidaza · 12053482 · Method of Use · US
- — Vidaza · 11571436 · Formulation · US
- — Vidaza · 8846628 · Formulation · US
Sponsor landscape (Actinomycin [EPC] class)
- Recordati · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Cosmegen — Competitive Intelligence Brief. https://druglandscape.com/ci/dactinomycin. Accessed 2026-05-14.
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