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CZP — Competitive Intelligence Brief
phase 3
TNF-α inhibitor
TNF-α (Tumor Necrosis Factor-alpha)
Immunology
Small molecule
Live · refreshed every 30 min
Target snapshot
CZP (CZP) — Astellas Pharma Inc. CZP is a humanized monoclonal antibody that binds to and neutralizes tumor necrosis factor-alpha (TNF-α), reducing inflammatory signaling.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| CZP TARGET | CZP | Astellas Pharma Inc | phase 3 | TNF-α inhibitor | TNF-α (Tumor Necrosis Factor-alpha) | |
| Humira® (Adalimumab) | Humira® (Adalimumab) | Mylan Inc. | marketed | TNF-α inhibitor (monoclonal antibody) | TNF-α (Tumor Necrosis Factor-alpha) | |
| infliximab therapeutic drug monitoring | infliximab therapeutic drug monitoring | Imelda GI Clinical Research Center | marketed | TNF-α inhibitor (monoclonal antibody) | TNF-α (tumor necrosis factor-alpha) | |
| Adalimumab (ADA) | Adalimumab (ADA) | JHSPH Center for Clinical Trials | marketed | TNF-α inhibitor (monoclonal antibody) | TNF-α (tumor necrosis factor-alpha) | |
| SB5 (Adalimumab Biosimilar) | SB5 (Adalimumab Biosimilar) | Samsung Bioepis Co., Ltd. | marketed | TNF-α inhibitor (monoclonal antibody biosimilar) | TNF-α (tumor necrosis factor-alpha) | |
| Infliximab biosimilar | Infliximab biosimilar | Hanyang University Seoul Hospital | marketed | TNF-α inhibitor (monoclonal antibody) | TNF-α (tumor necrosis factor-alpha) | |
| Akkermansia muciniphila + Infliximab | Akkermansia muciniphila + Infliximab | Chinese Medical Association | marketed | Combination therapy: probiotic + TNF-α inhibitor | TNF-α (infliximab component); gut microbiota modulation (Akkermansia muciniphila component) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (TNF-α inhibitor class)
- Abbott · 1 drug in this class
- Alvotech Swiss AG · 1 drug in this class
- Astellas Pharma Inc · 1 drug in this class
- Innovaderm Research Inc. · 1 drug in this class
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- Whole TNF-α inhibitor class — RSS
Cite this brief
Drug Landscape (2026). CZP — Competitive Intelligence Brief. https://druglandscape.com/ci/czp. Accessed 2026-05-15.
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