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CZP — Competitive Intelligence Brief

CZP (CZP) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: TNF-α inhibitor. Area: Immunology.

phase 3 TNF-α inhibitor TNF-α (Tumor Necrosis Factor-alpha) Immunology Small molecule Live · refreshed every 30 min

Target snapshot

CZP (CZP) — Astellas Pharma Inc. CZP is a humanized monoclonal antibody that binds to and neutralizes tumor necrosis factor-alpha (TNF-α), reducing inflammatory signaling.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
CZP TARGET CZP Astellas Pharma Inc phase 3 TNF-α inhibitor TNF-α (Tumor Necrosis Factor-alpha)
Humira® (Adalimumab) Humira® (Adalimumab) Mylan Inc. marketed TNF-α inhibitor (monoclonal antibody) TNF-α (Tumor Necrosis Factor-alpha)
infliximab therapeutic drug monitoring infliximab therapeutic drug monitoring Imelda GI Clinical Research Center marketed TNF-α inhibitor (monoclonal antibody) TNF-α (tumor necrosis factor-alpha)
Adalimumab (ADA) Adalimumab (ADA) JHSPH Center for Clinical Trials marketed TNF-α inhibitor (monoclonal antibody) TNF-α (tumor necrosis factor-alpha)
SB5 (Adalimumab Biosimilar) SB5 (Adalimumab Biosimilar) Samsung Bioepis Co., Ltd. marketed TNF-α inhibitor (monoclonal antibody biosimilar) TNF-α (tumor necrosis factor-alpha)
Infliximab biosimilar Infliximab biosimilar Hanyang University Seoul Hospital marketed TNF-α inhibitor (monoclonal antibody) TNF-α (tumor necrosis factor-alpha)
Akkermansia muciniphila + Infliximab Akkermansia muciniphila + Infliximab Chinese Medical Association marketed Combination therapy: probiotic + TNF-α inhibitor TNF-α (infliximab component); gut microbiota modulation (Akkermansia muciniphila component)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (TNF-α inhibitor class)

  1. Abbott · 1 drug in this class
  2. Alvotech Swiss AG · 1 drug in this class
  3. Astellas Pharma Inc · 1 drug in this class
  4. Innovaderm Research Inc. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). CZP — Competitive Intelligence Brief. https://druglandscape.com/ci/czp. Accessed 2026-05-15.

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