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Cyclosporine 0.010% eye drops — Competitive Intelligence Brief
phase 2
Calcineurin inhibitor
Calcineurin
Immunology
Small molecule
Live · refreshed every 30 min
Target snapshot
Cyclosporine 0.010% eye drops (Cyclosporine 0.010% eye drops) — Allergan. Cyclosporine is an immunosuppressant that inhibits calcineurin, thereby reducing T-cell activation.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Cyclosporine 0.010% eye drops TARGET | Cyclosporine 0.010% eye drops | Allergan | phase 2 | Calcineurin inhibitor | Calcineurin | |
| Sandimmune | cyclosporine | Novartis AG (originally Sandoz) | marketed | Calcineurin inhibitor (immunosuppressant) | Calcineurin subunit B type 1, Canalicular multispecific organic anion transporter 1, Canalicular multispecific organic anion transporter 2 | 1983-11-14 |
| CYCLOSPORINE | CYCLOSPORINE | marketed | Calcineurin Inhibitor Immunosuppressant [EPC] | calcineurin | 1983-01-01 | |
| Cyclosporine A eye drops 0.5% | Cyclosporine A eye drops 0.5% | Military Hospital of Tunis | marketed | Calcineurin inhibitor | Calcineurin (protein phosphatase 2B) | |
| tacrolimus, ATG | tacrolimus, ATG | University Hospital, Toulouse | marketed | Calcineurin inhibitor and polyclonal antithymocyte antibody | Calcineurin (tacrolimus); T-cell surface antigens including CD2, CD3, CD4, CD8, CD25 (ATG) | |
| Tacrolimus, Accord | Tacrolimus, Accord | University of Cincinnati | marketed | Calcineurin inhibitor | Calcineurin (via FKBP12 binding) | |
| Tacrolimus and Everolimus | Tacrolimus and Everolimus | Chang Gung Memorial Hospital | marketed | Immunosuppressant (calcineurin inhibitor and mTOR inhibitor combination) | Calcineurin (tacrolimus) and mTOR (everolimus) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
- — Sandimmune · 8298568 · Formulation · US
- — Sandimmune · 9132071 · Formulation · US
- — Sandimmune · 8614178 · Formulation · US
- — Sandimmune · 8292129 · Formulation · US
- — Sandimmune · 8561859 · Formulation · US
- — Sandimmune · 8980839 · Formulation · US
- — Sandimmune · 10441630 · Formulation · US
- — Sandimmune · 9937225 · Formulation · US
- — Sandimmune · 9676525 · Formulation · US
- — Sandimmune · 9669974 · Formulation · US
- — Sandimmune · 12496326 · Method of Use · US
- — Sandimmune · 11951153 · Method of Use · US
- — Sandimmune · 10918694 · Formulation · US
- — Sandimmune · 10813976 · Formulation · US
- — Sandimmune · 11154513 · Formulation · US
- — Sandimmune · 11413323 · Method of Use · US
- — Sandimmune · 12059449 · Formulation · US
Sponsor landscape (Calcineurin inhibitor class)
- Novartis · 4 drugs in this class
- Astellas Pharma Inc · 4 drugs in this class
- Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd. · 4 drugs in this class
- University of Cincinnati · 3 drugs in this class
- Allergan · 3 drugs in this class
- Astellas Pharma China, Inc. · 3 drugs in this class
- Novaliq GmbH · 3 drugs in this class
- Hoffmann-La Roche · 3 drugs in this class
- LEO Pharma · 3 drugs in this class
- Santen SAS · 3 drugs in this class
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Cite this brief
Drug Landscape (2026). Cyclosporine 0.010% eye drops — Competitive Intelligence Brief. https://druglandscape.com/ci/cyclosporine-0-010-eye-drops. Accessed 2026-05-18.
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