Who are Cytoxan (Lyophilized)'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Paraplatin, Mitomycin C, Busulfan (BU), Cyclophosphamide (CY), CYC, Mitomycin C 0.02%.

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Last reviewed 2026-05-13 · How we verify

Cytoxan (Lyophilized) — Competitive Intelligence Brief

Cytoxan (Lyophilized) (cyclophosphamide) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Alkylating agent. Area: Oncology.

marketed Alkylating agent Tumor cell DNA Oncology Live · refreshed every 30 min

Target snapshot

Cytoxan (Lyophilized) (cyclophosphamide) — Baxter. Cyclophosphamide cross-links tumor cell DNA and interferes with malignant cell growth through active alkylating metabolites.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Cytoxan (Lyophilized) TARGET	cyclophosphamide	Baxter	marketed	Alkylating agent	Tumor cell DNA	1959-01-01
Paraplatin	Carboplatin	MYLAN SEIYAKU Ltd	marketed	Platinum-containing alkylating agent	DNA	1989-01-01
Mitomycin C	Mitomycin C	University of Erlangen-Nürnberg Medical School	marketed	DNA alkylating agent	DNA
Busulfan (BU)	Busulfan (BU)	Nanfang Hospital, Southern Medical University	marketed	Alkylating agent	DNA (non-specific alkylation)
Cyclophosphamide (CY)	Cyclophosphamide (CY)	Nanfang Hospital, Southern Medical University	marketed	Alkylating agent	DNA (non-specific alkylation)
CYC	CYC	Italian Sarcoma Group	marketed	Alkylating agent	DNA
Mitomycin C 0.02%	Mitomycin C 0.02%	Shahid Beheshti University of Medical Sciences	marketed	Alkylating agent	DNA

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2035-06-26 — Cytoxan (Lyophilized) · 9662342 · Formulation · US
2035-07-13 — Cytoxan (Lyophilized) · 10849916 · Formulation · US
2035-12-01 — Cytoxan (Lyophilized) · 11382923 · Formulation · US
2036-02-15 — Cytoxan (Lyophilized) · 12329767 · Formulation · US
2036-02-15 — Cytoxan (Lyophilized) · 10993952 · Formulation · US

Sponsor landscape (Alkylating agent class)

Assistance Publique - Hôpitaux de Paris · 2 drugs in this class
M.D. Anderson Cancer Center · 2 drugs in this class
Nanfang Hospital, Southern Medical University · 2 drugs in this class
Asahi Kasei Pharma Corporation · 1 drug in this class
Baxter · 1 drug in this class
BeBetter Med Inc · 1 drug in this class
Astellas Pharma China, Inc. · 1 drug in this class
Children's Cancer Group, China · 1 drug in this class
Federal Research Institute of Pediatric Hematology, Oncology and Immunology · 1 drug in this class
Celyad Oncology SA · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Cytoxan (Lyophilized) — Competitive Intelligence Brief. https://druglandscape.com/ci/cyclophosphamide. Accessed 2026-05-13.

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