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Alexion Pharmaceuticals, Inc. — Portfolio Competitive Intelligence Brief

Alexion Pharmaceuticals, Inc. pipeline: 1 marketed, 0 filed, 5 Phase 3, 8 Phase 2. Recent regulatory actions, upcoming PDUFA, patent timeline, top competitor overlap.

1 marketed 0 filed 5 Phase 3 8 Phase 2 35 Phase 1 Live · 30-min refresh

Portfolio leaders (marketed + Phase 3 / filed)

DrugGenericPhaseClassTargetAreaFirst approval
Ultomiris Ultomiris marketed Complement C5 Other
ALXN1850 ALXN1850 phase 3 Complement C3 inhibitor Complement C3 Nephrology / Immunology
ALXN2060 ALXN2060 phase 3 Complement C3 inhibitor Complement C3 Immunology / Hematology
C5 Inhibitor C5 Inhibitor phase 3 Complement C5 inhibitor C5 Immunology
CAEL-101 CAEL-101 phase 3 Transthyretin (TTR) stabilizer Transthyretin (TTR) Rare Disease / Amyloidosis
pexelizumab in conjunction with CABG pexelizumab in conjunction with CABG phase 3 Monoclonal antibody Complement component 5 (C5) Cardiovascular

Therapeutic area mix

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this portfolio.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this portfolio.

Patent timeline (forward window)

No upcoming patent expiries for this portfolio.

Competitive overlap (companies sharing drug classes)

  1. Sanofi · 2 shared drug classes
  2. CSL Behring · 2 shared drug classes
  3. Hoffmann-La Roche · 2 shared drug classes
  4. Pfizer Inc. · 2 shared drug classes
  5. Arbeitsgemeinschaft medikamentoese Tumortherapie · 1 shared drug class
  6. Assistance Publique - Hôpitaux de Paris · 1 shared drug class
  7. Aldeyra Therapeutics, Inc. · 1 shared drug class
  8. Apellis Pharmaceuticals, Inc. · 1 shared drug class

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Cite this brief

Drug Landscape (2026). Alexion Pharmaceuticals, Inc. — Portfolio Competitive Intelligence Brief. https://druglandscape.com/ci/company/alexion-pharmaceuticals-inc. Accessed 2026-05-16.

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