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Combination of prednisone and azathioprine — Competitive Intelligence Brief

Combination of prednisone and azathioprine (Combination of prednisone and azathioprine) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Immunosuppressant combination. Area: Immunology.

phase 3 Immunosuppressant combination Immunology Small molecule Live · refreshed every 30 min

Target snapshot

Combination of prednisone and azathioprine (Combination of prednisone and azathioprine) — St. Anne's University Hospital Brno, Czech Republic. This combination suppresses the immune system by reducing corticosteroid-mediated inflammation and blocking T-cell proliferation through azathioprine's purine antagonism.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Combination of prednisone and azathioprine TARGET Combination of prednisone and azathioprine St. Anne's University Hospital Brno, Czech Republic phase 3 Immunosuppressant combination
Ciclosporin and Mycophenolate-mofetil Ciclosporin and Mycophenolate-mofetil University of Giessen marketed Immunosuppressant combination Calcineurin (ciclosporin); IMPDH type II (mycophenolate mofetil)
infliximab+azathioprine infliximab+azathioprine Belgian Inflammatory Bowel Disease Research and Development (BIRD) VZW marketed TNF-α inhibitor + immunosuppressant combination TNF-α receptor (infliximab); purine metabolism (azathioprine)
XR-tacrolimus QD + MMF BID then MMF QD XR-tacrolimus QD + MMF BID then MMF QD University Hospital, Limoges marketed Calcineurin inhibitor + Antimetabolite immunosuppressant combination Calcineurin (tacrolimus); Inosine monophosphate dehydrogenase (mycophenolate mofetil)
Systemic corticosteroids/methotrexate Systemic corticosteroids/methotrexate Merck KGaA, Darmstadt, Germany marketed Immunosuppressant combination (corticosteroid + DMARD) Glucocorticoid receptor (corticosteroids); dihydrofolate reductase (methotrexate)
Tacrolimus/MMF Tacrolimus/MMF University of Miami marketed Immunosuppressant combination Calcineurin (tacrolimus); IMPDH type II (MMF)
XR-tacrolimus QD + MMF BID XR-tacrolimus QD + MMF BID University Hospital, Limoges marketed Calcineurin inhibitor + Antimetabolite immunosuppressant combination Calcineurin (tacrolimus); IMPDH type II (mycophenolate mofetil)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Immunosuppressant combination class)

  1. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · 1 drug in this class
  2. St. Anne's University Hospital Brno, Czech Republic · 1 drug in this class
  3. Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan · 1 drug in this class
  4. University of Giessen · 1 drug in this class
  5. University of Miami · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Combination of prednisone and azathioprine — Competitive Intelligence Brief. https://druglandscape.com/ci/combination-of-prednisone-and-azathioprine. Accessed 2026-05-17.

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