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Combination of prednisone and azathioprine — Competitive Intelligence Brief
phase 3
Immunosuppressant combination
Immunology
Small molecule
Live · refreshed every 30 min
Target snapshot
Combination of prednisone and azathioprine (Combination of prednisone and azathioprine) — St. Anne's University Hospital Brno, Czech Republic. This combination suppresses the immune system by reducing corticosteroid-mediated inflammation and blocking T-cell proliferation through azathioprine's purine antagonism.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Combination of prednisone and azathioprine TARGET | Combination of prednisone and azathioprine | St. Anne's University Hospital Brno, Czech Republic | phase 3 | Immunosuppressant combination | ||
| Ciclosporin and Mycophenolate-mofetil | Ciclosporin and Mycophenolate-mofetil | University of Giessen | marketed | Immunosuppressant combination | Calcineurin (ciclosporin); IMPDH type II (mycophenolate mofetil) | |
| infliximab+azathioprine | infliximab+azathioprine | Belgian Inflammatory Bowel Disease Research and Development (BIRD) VZW | marketed | TNF-α inhibitor + immunosuppressant combination | TNF-α receptor (infliximab); purine metabolism (azathioprine) | |
| XR-tacrolimus QD + MMF BID then MMF QD | XR-tacrolimus QD + MMF BID then MMF QD | University Hospital, Limoges | marketed | Calcineurin inhibitor + Antimetabolite immunosuppressant combination | Calcineurin (tacrolimus); Inosine monophosphate dehydrogenase (mycophenolate mofetil) | |
| Systemic corticosteroids/methotrexate | Systemic corticosteroids/methotrexate | Merck KGaA, Darmstadt, Germany | marketed | Immunosuppressant combination (corticosteroid + DMARD) | Glucocorticoid receptor (corticosteroids); dihydrofolate reductase (methotrexate) | |
| Tacrolimus/MMF | Tacrolimus/MMF | University of Miami | marketed | Immunosuppressant combination | Calcineurin (tacrolimus); IMPDH type II (MMF) | |
| XR-tacrolimus QD + MMF BID | XR-tacrolimus QD + MMF BID | University Hospital, Limoges | marketed | Calcineurin inhibitor + Antimetabolite immunosuppressant combination | Calcineurin (tacrolimus); IMPDH type II (mycophenolate mofetil) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Immunosuppressant combination class)
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · 1 drug in this class
- St. Anne's University Hospital Brno, Czech Republic · 1 drug in this class
- Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan · 1 drug in this class
- University of Giessen · 1 drug in this class
- University of Miami · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Combination of prednisone and azathioprine — Competitive Intelligence Brief. https://druglandscape.com/ci/combination-of-prednisone-and-azathioprine. Accessed 2026-05-17.
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