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combination of Ketamine and Propofol — Competitive Intelligence Brief
phase 3
Anesthetic
NMDA receptor
Anesthesiology
Small molecule
Live · refreshed every 30 min
Target snapshot
combination of Ketamine and Propofol (combination of Ketamine and Propofol) — Nantes University Hospital. Ketamine and Propofol work together to induce general anesthesia by modulating NMDA receptors and inhibiting GABA uptake.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| combination of Ketamine and Propofol TARGET | combination of Ketamine and Propofol | Nantes University Hospital | phase 3 | Anesthetic | NMDA receptor | |
| Namenda | MEMANTINE | AbbVie | marketed | N-methyl-D-aspartate Receptor Antagonist | Glutamate NMDA receptor; GRIN1/GRIN2A | 2003-01-01 |
| Felbatol | FELBAMATE | Mylan Speciality Lp | marketed | Anti-epileptic Agent [EPC] | NMDA receptor-ionophore complex | 1993-01-01 |
| QUINIDINE | QUINIDINE | marketed | sigma-1 receptor, NMDA receptor, CYP2D6 | 1950-01-01 | ||
| Methadone Hydrochloride | METHADONE | Specgx Llc | marketed | Opioid Agonist | mu-opioid receptors, NMDA receptor | 1947-01-01 |
| Intravenous anesthetic | Intravenous anesthetic | University of Pennsylvania | marketed | GABA-A receptor agonist / NMDA receptor antagonist (class-dependent) | GABA-A receptor or NMDA receptor (varies by specific agent) | |
| Ketamine plus usual care | Ketamine plus usual care | The University of Texas Health Science Center, Houston | marketed | NMDA receptor antagonist | NMDA receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Anesthetic class)
- Express Specialty Pharmacy · 1 drug in this class
- Nantes University Hospital · 1 drug in this class
- The University of Texas Health Science Center, Houston · 1 drug in this class
- Universidad de Colima · 1 drug in this class
- University Hospital, Montpellier · 1 drug in this class
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Cite this brief
Drug Landscape (2026). combination of Ketamine and Propofol — Competitive Intelligence Brief. https://druglandscape.com/ci/combination-of-ketamine-and-propofol. Accessed 2026-05-18.
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