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Chlorpheniramine maleate syrup — Competitive Intelligence Brief

Chlorpheniramine maleate syrup (Chlorpheniramine maleate syrup) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: H1 receptor antagonist (first-generation antihistamine). Area: Allergy/Immunology.

phase 3 H1 receptor antagonist (first-generation antihistamine) Histamine H1 receptor Allergy/Immunology Small molecule Live · refreshed every 30 min

Target snapshot

Chlorpheniramine maleate syrup (Chlorpheniramine maleate syrup) — Organon and Co. Chlorpheniramine maleate blocks histamine H1 receptors to reduce allergic symptoms and itching.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Chlorpheniramine maleate syrup TARGET Chlorpheniramine maleate syrup Organon and Co phase 3 H1 receptor antagonist (first-generation antihistamine) Histamine H1 receptor
Lastacaft ALCAFTADINE AbbVie marketed Histamine-1 Receptor Antagonist [EPC] Histamine H1 receptor 2010-01-01
Xyzal LEVOCETIRIZINE Sanofi marketed Histamine-1 Receptor Antagonist Histamine H1 receptor 2007-01-01
Elestat EPINASTINE AbbVie marketed Adrenergic Receptor Agonist Histamine H1 receptor 2003-01-01
Rupax RUPATADINE Teikoku Seiyaku marketed rupatadine Histamine H1 receptor 2001-01-01
Zaditor KETOTIFEN marketed Histamine-1 Receptor Inhibitor Histamine H1 receptor 1999-01-01
Mizollen MIZOLASTINE Sanofi marketed mizolastine Histamine H1 receptor 1998-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (H1 receptor antagonist (first-generation antihistamine) class)

  1. Federal State Budgetary Scientific Institution, Research Institute of Fundamental and Clinical Immunology · 1 drug in this class
  2. Organon and Co · 1 drug in this class
  3. Sanofi · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Chlorpheniramine maleate syrup — Competitive Intelligence Brief. https://druglandscape.com/ci/chlorpheniramine-maleate-syrup. Accessed 2026-05-17.

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