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Chlorothiazide Injection — Competitive Intelligence Brief
marketed
Thiazide diuretic
Sodium-chloride cotransporter (NCC)
Cardiovascular
Small molecule
Live · refreshed every 30 min
Target snapshot
Chlorothiazide Injection (Chlorothiazide Injection) — University of Virginia. Chlorothiazide inhibits sodium chloride reabsorption in the distal convoluted tubule of the nephron, promoting urinary excretion of sodium, chloride, and water.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Chlorothiazide Injection TARGET | Chlorothiazide Injection | University of Virginia | marketed | Thiazide diuretic | Sodium-chloride cotransporter (NCC) | |
| olmesartan medoxomil-hydrochlorothiazide | OLMESARTAN | Cosette | marketed | Thiazide Diuretic [EPC] | 2019-01-01 | |
| Benicar | OLMESARTAN MEDOXOMIL | Cosette | marketed | Thiazide Diuretic [EPC] | Type-1 angiotensin II receptor | 2002-01-01 |
| Zestril | lisinopril | Generic (originally Merck/AstraZeneca) | marketed | Thiazide Diuretic [EPC] | Angiotensin-converting enzyme, Angiotensin-converting enzyme | 1987-12-29 |
| Capozide 25/15 | CAPTOPRIL | Aarxion Anda Hlding | marketed | Thiazide Diuretic [EPC] | Renin | 1981-01-01 |
| TRIAMTERENE | TRIAMTERENE | marketed | Thiazide Diuretic [EPC] | 1964-01-01 | ||
| Enduron | methylclothiazide | marketed | Thiazide Diuretic | Solute carrier family 12 member 3 | 1960-01-01 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
- — Zestril · 9616096 · Method of Use · US
- — Zestril · 10039800 · Method of Use · US
- — Zestril · 10406199 · Method of Use · US
- — Zestril · 12433931 · Method of Use · US
- — Zestril · 10265370 · Formulation · US
- — Zestril · 9463183 · Formulation · US
- — Zestril · 11179434 · Formulation · US
- — Zestril · 9814751 · Formulation · US
- — Zestril · 10940177 · Formulation · US
- — Zestril · 11771733 · Formulation · US
- — Zestril · 12186360 · Formulation · US
- — Zestril · 12128083 · Formulation · US
Sponsor landscape (Thiazide diuretic class)
- Cedars-Sinai Medical Center · 2 drugs in this class
- National University of Ireland, Galway, Ireland · 1 drug in this class
- Bristol-Myers Squibb · 1 drug in this class
- Seiji Umemoto, M.D., Ph.D. · 1 drug in this class
- Takeda · 1 drug in this class
- University of Virginia · 1 drug in this class
- Novartis · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Chlorothiazide Injection — Competitive Intelligence Brief. https://druglandscape.com/ci/chlorothiazide-injection. Accessed 2026-05-14.
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