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CEP-10953 (Armodafinil) — Competitive Intelligence Brief
phase 3
Wakefulness-promoting agent
Dopamine transporter (DAT)
Neurology / Sleep Medicine
Small molecule
Live · refreshed every 30 min
Target snapshot
CEP-10953 (Armodafinil) (CEP-10953 (Armodafinil)) — Cephalon. Armodafinil promotes wakefulness by increasing dopamine levels in the brain, likely through dopamine reuptake inhibition and other monoaminergic pathways.
Comparator set (3 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| CEP-10953 (Armodafinil) TARGET | CEP-10953 (Armodafinil) | Cephalon | phase 3 | Wakefulness-promoting agent | Dopamine transporter (DAT) | |
| cognitive function | cognitive function | Huazhong University of Science and Technology | marketed | wakefulness-promoting agent | ||
| modafinil (M1, M2, M4) | modafinil (M1, M2, M4) | University of California, Los Angeles | marketed | Eugeroic (wakefulness-promoting agent) | Dopamine transporter (DAT); norepinephrine transporter (NET); orexin system modulation | |
| DOCETAXEL(XRP6976) + MODAFINIL | DOCETAXEL(XRP6976) + MODAFINIL | Sanofi | phase 3 | Taxane chemotherapy + wakefulness-promoting agent combination | β-tubulin (docetaxel); dopamine/norepinephrine/histamine systems (modafinil) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Wakefulness-promoting agent class)
- Cephalon · 1 drug in this class
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Cite this brief
Drug Landscape (2026). CEP-10953 (Armodafinil) — Competitive Intelligence Brief. https://druglandscape.com/ci/cep-10953-armodafinil. Accessed 2026-05-17.
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