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cognitive function

Huazhong University of Science and Technology · FDA-approved active Small molecule

Modafinil works by increasing the levels of certain neurotransmitters in the brain, such as dopamine and norepinephrine, which helps to improve alertness and wakefulness.

Modafinil works by increasing the levels of certain neurotransmitters in the brain, such as dopamine and norepinephrine, which helps to improve alertness and wakefulness. Used for Narcolepsy, Obstructive sleep apnea, Shift work sleep disorder.

At a glance

Generic namecognitive function
SponsorHuazhong University of Science and Technology
Drug classwakefulness-promoting agent
ModalitySmall molecule
Therapeutic areaNeurology
PhaseFDA-approved

Mechanism of action

Modafinil is believed to exert its effects by increasing the release of these neurotransmitters, which helps to regulate the sleep-wake cycle and improve cognitive function. This is thought to occur through the activation of certain receptors in the brain, including the dopamine and norepinephrine transporters.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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