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CCB use — Competitive Intelligence Brief

CCB use (CCB use) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Calcium channel blocker. Area: Cardiovascular.

phase 2 Calcium channel blocker L-type calcium channels Cardiovascular Small molecule Live · refreshed every 30 min

Target snapshot

CCB use (CCB use) — GlaxoSmithKline. CCBs work by inhibiting the L-type calcium channels in the heart and vascular smooth muscle, leading to vasodilation and reduced cardiac workload.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
CCB use TARGET CCB use GlaxoSmithKline phase 2 Calcium channel blocker L-type calcium channels
Lotrel (amlodipine/benazepril) Lotrel (amlodipine/benazepril) Abbott marketed Calcium channel blocker / ACE inhibitor combination L-type calcium channels (amlodipine); Angiotensin-converting enzyme (benazepril)
DHP DHP Centro de Investigacao em Saude de Manhica marketed calcium channel blocker L-type calcium channels
losartan/amlodpine losartan/amlodpine University of Pavia marketed Angiotensin II receptor blocker (ARB) / Calcium channel blocker (CCB) Angiotensin II receptors (AT1) and L-type calcium channels
Verapamil Hydrochloride Verapamil Hydrochloride Pfizer Inc. marketed Calcium channel blocker L-type calcium channels (slow channels)
Phase B: Triplixam / Elestar HCT Phase B: Triplixam / Elestar HCT National Institute of Cardiology, Warsaw, Poland marketed Fixed-dose combination antihypertensive (calcium channel blocker + ARB + thiazide diuretic) L-type calcium channels, angiotensin II type 1 receptor (AT1R), sodium-chloride cotransporter
Magnesium sulfate IV Magnesium sulfate IV University of Liege marketed Electrolyte supplement / anticonvulsant NMDA receptor, L-type calcium channels

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Calcium channel blocker class)

  1. Shenzhen Ausa Pharmed Co.,Ltd · 2 drugs in this class
  2. Boryung Pharmaceutical Co., Ltd · 2 drugs in this class
  3. Ain Shams University · 1 drug in this class
  4. Bioprojet · 1 drug in this class
  5. Bristol-Myers Squibb · 1 drug in this class
  6. GlaxoSmithKline · 1 drug in this class
  7. Handok Inc. · 1 drug in this class
  8. Hasten Biopharmaceutical Co., Ltd. · 1 drug in this class
  9. Hospital de Clinicas de Porto Alegre · 1 drug in this class
  10. Laboratorios Richmond S.A.C.I.F. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). CCB use — Competitive Intelligence Brief. https://druglandscape.com/ci/ccb-use. Accessed 2026-05-13.

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