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CC-42344 — Competitive Intelligence Brief
phase 2
SARS-CoV-2 main protease inhibitor
SARS-CoV-2 main protease
Infectious Disease
Small molecule
Live · refreshed every 30 min
Target snapshot
CC-42344 (CC-42344) — Cocrystal Pharma, Inc.. CC-42344 is a small molecule inhibitor of the SARS-CoV-2 main protease.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| CC-42344 TARGET | CC-42344 | Cocrystal Pharma, Inc. | phase 2 | SARS-CoV-2 main protease inhibitor | SARS-CoV-2 main protease | |
| Paxlovid (Copackaged) | Nirmatrelvir | Pfizer | marketed | Antiviral protease inhibitor | SARS-CoV-2 main protease (Mpro, 3CLpro, nsp5 protease) | 2023-01-01 |
| Pf-07817883 | pf-07817883 | Pfizer | marketed | Protease inhibitor | SARS-CoV-2 main protease | |
| Ximingting Tablet | Ximingting Tablet | Peking Union Medical College Hospital | marketed | SARS-CoV-2 main protease inhibitor | SARS-CoV-2 main protease | |
| ibuzatrelvir | ibuzatrelvir | Pfizer | marketed | Antiviral | SARS-CoV-2 main protease (Mpro) | |
| (E) BQ-V14 | (E) BQ-V14 | National Taiwan University Hospital | marketed | SARS-CoV-2 main protease inhibitor | SARS-CoV-2 main protease | |
| PF-07321332 Dose 1 | pf-07321332-dose-1 | Pfizer | marketed | Protease inhibitor | SARS-CoV-2 main protease (Mpro) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
- — Paxlovid (Copackaged) · 11351149 · US
- — Paxlovid (Copackaged) · 11541034 · US
Sponsor landscape (SARS-CoV-2 main protease inhibitor class)
- Cocrystal Pharma, Inc. · 2 drugs in this class
- Ahn-Gook Pharmaceuticals Co.,Ltd · 1 drug in this class
- Beijing Minhai Biotechnology Co., Ltd · 1 drug in this class
- Biota Scientific Management Pty Ltd · 1 drug in this class
- Ethris GmbH · 1 drug in this class
- IRCCS San Raffaele · 1 drug in this class
- Icahn School of Medicine at Mount Sinai · 1 drug in this class
- National Taiwan University Hospital · 1 drug in this class
- Peking Union Medical College Hospital · 1 drug in this class
- RSV Therapeutics LLC · 1 drug in this class
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- Whole SARS-CoV-2 main protease inhibitor class — RSS
Cite this brief
Drug Landscape (2026). CC-42344 — Competitive Intelligence Brief. https://druglandscape.com/ci/cc-42344. Accessed 2026-05-13.
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