Who are carboplatin, thiotepa, and cyclophosphamide's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Paraplatin, Cytoxan (Lyophilized), Melphalan Injection, Bus and Dex, prednisone plus cyclophosphamide, IFO.

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Last reviewed 2026-05-16 · How we verify

carboplatin, thiotepa, and cyclophosphamide — Competitive Intelligence Brief

carboplatin, thiotepa, and cyclophosphamide (carboplatin, thiotepa, and cyclophosphamide) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Alkylating agent. Area: Oncology.

phase 3 Alkylating agent Oncology Small molecule Live · refreshed every 30 min

Target snapshot

carboplatin, thiotepa, and cyclophosphamide (carboplatin, thiotepa, and cyclophosphamide) — The Netherlands Cancer Institute. Carboplatin, thiotepa, and cyclophosphamide work by interfering with DNA replication and function, leading to cell death in rapidly dividing cancer cells.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
carboplatin, thiotepa, and cyclophosphamide TARGET	carboplatin, thiotepa, and cyclophosphamide	The Netherlands Cancer Institute	phase 3	Alkylating agent
Paraplatin	Carboplatin	MYLAN SEIYAKU Ltd	marketed	Platinum-containing alkylating agent	DNA	1989-01-01
Cytoxan (Lyophilized)	cyclophosphamide	Baxter	marketed	Alkylating agent	Tumor cell DNA	1959-01-01
Melphalan Injection	Melphalan Injection	Hospital das Clínicas de Ribeirão Preto	marketed	Alkylating agent	DNA
Bus and Dex	Bus and Dex	The Cleveland Clinic	marketed	Alkylating agent + corticosteroid combination
prednisone plus cyclophosphamide	prednisone plus cyclophosphamide	Guangdong Provincial People's Hospital	marketed	Corticosteroid plus alkylating agent combination
IFO	IFO	Italian Sarcoma Group	marketed	Alkylating Agent	DNA

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2035-06-26 — Cytoxan (Lyophilized) · 9662342 · Formulation · US
2035-07-13 — Cytoxan (Lyophilized) · 10849916 · Formulation · US
2035-12-01 — Cytoxan (Lyophilized) · 11382923 · Formulation · US
2036-02-15 — Cytoxan (Lyophilized) · 12329767 · Formulation · US
2036-02-15 — Cytoxan (Lyophilized) · 10993952 · Formulation · US

Sponsor landscape (Alkylating agent class)

Assistance Publique - Hôpitaux de Paris · 2 drugs in this class
M.D. Anderson Cancer Center · 2 drugs in this class
Nanfang Hospital, Southern Medical University · 2 drugs in this class
Asahi Kasei Pharma Corporation · 1 drug in this class
Baxter · 1 drug in this class
BeBetter Med Inc · 1 drug in this class
Astellas Pharma China, Inc. · 1 drug in this class
Children's Cancer Group, China · 1 drug in this class
Federal Research Institute of Pediatric Hematology, Oncology and Immunology · 1 drug in this class
Celyad Oncology SA · 1 drug in this class

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Cite this brief

Drug Landscape (2026). carboplatin, thiotepa, and cyclophosphamide — Competitive Intelligence Brief. https://druglandscape.com/ci/carboplatin-thiotepa-and-cyclophosphamide. Accessed 2026-05-16.

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