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Last reviewed 2026-06-10 · How we verify

Captopril,Hydrochlorothiazide — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Captopril,Hydrochlorothiazide (Captopril,Hydrochlorothiazide) competitive landscape: 1 comparator, recent regulatory actions, upcoming PDUFA, patent timeline. Class: ACE inhibitor + thiazide diuretic combination. Area: Cardiovascular.

marketed ACE inhibitor + thiazide diuretic combination ACE (angiotensin-converting enzyme); sodium-chloride cotransporter in distal convoluted tubule Cardiovascular Small molecule Live · refreshed every 30 min

Target snapshot

Captopril,Hydrochlorothiazide (Captopril,Hydrochlorothiazide) — West China Hospital. This combination reduces blood pressure by inhibiting angiotensin-converting enzyme (ACE) to dilate blood vessels and promoting sodium and water excretion through diuretic action.

Comparator set (1 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Captopril,Hydrochlorothiazide TARGET	Captopril,Hydrochlorothiazide	West China Hospital	marketed	ACE inhibitor + thiazide diuretic combination	ACE (angiotensin-converting enzyme); sodium-chloride cotransporter in distal convoluted tubule
Lisinopril + HCTZ	Lisinopril + HCTZ	St. Paul Heart Clinic	phase 3	ACE inhibitor + thiazide diuretic combination	Angiotensin-converting enzyme (ACE); sodium-chloride cotransporter (NCCT)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (ACE inhibitor + thiazide diuretic combination class)

St. Paul Heart Clinic · 1 drug in this class
West China Hospital · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Captopril,Hydrochlorothiazide — Competitive Intelligence Brief. https://druglandscape.com/ci/captopril-hydrochlorothiazide. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing