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Capecitabine plus temozolomide VS Capecitabine — Competitive Intelligence Brief
phase 2
Antineoplastic agent
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Capecitabine plus temozolomide VS Capecitabine (Capecitabine plus temozolomide VS Capecitabine) — Asan Medical Center. Capecitabine is a prodrug that is converted into 5-fluorouracil, which interferes with DNA synthesis, thereby inhibiting cancer cell growth. Temozolomide works by methylating DNA, which triggers cell death in rapidly dividing cancer cells.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Capecitabine plus temozolomide VS Capecitabine TARGET | Capecitabine plus temozolomide VS Capecitabine | Asan Medical Center | phase 2 | Antineoplastic agent | ||
| Liposomal doxorubicin hydrochloride | Liposomal doxorubicin hydrochloride | Cephalon, Inc. | marketed | Antineoplastic agent | DNA and topoisomerase II | |
| TS-1 and cisplatin | TS-1 and cisplatin | Taiho Pharmaceutical Co., Ltd. | phase 3 | Antineoplastic agent | DNA | |
| S-1 [Tegafur/Oteracil/gimeracil] | S-1 [Tegafur/Oteracil/gimeracil] | AstraZeneca | phase 3 | Antineoplastic agent | Thymidylate synthase | |
| Pemetrexed + Cisplatin /Carboplatin | Pemetrexed + Cisplatin /Carboplatin | Jiangsu Hansoh Pharmaceutical Co., Ltd. | phase 3 | Antineoplastic agent | Thymidylate synthase, Dihydrofolate reductase, Glycinamide ribonucleotide formyltransferase | |
| cetuximab + cisplatin + vinorelbine | cetuximab + cisplatin + vinorelbine | Merck KGaA, Darmstadt, Germany | phase 3 | Antineoplastic agents | EGFR | |
| cytarabine and mitoxantrone | cytarabine and mitoxantrone | Pfizer | phase 3 | Antineoplastic agents |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antineoplastic agent class)
- Acrotech Biopharma Inc. · 1 drug in this class
- Asan Medical Center · 1 drug in this class
- AstraZeneca · 1 drug in this class
- Beijing Biostar Pharmaceuticals Co., Ltd. · 1 drug in this class
- Cephalon, Inc. · 1 drug in this class
- Jiangsu Hansoh Pharmaceutical Co., Ltd. · 1 drug in this class
- Seattle Project Corporation · 1 drug in this class
- Taiho Pharmaceutical Co., Ltd. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Capecitabine plus temozolomide VS Capecitabine — Competitive Intelligence Brief. https://druglandscape.com/ci/capecitabine-plus-temozolomide-vs-capecitabine. Accessed 2026-05-17.
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