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Candesartan+HCTZ - Phase 1 — Competitive Intelligence Brief

Candesartan+HCTZ - Phase 1 (Candesartan+HCTZ - Phase 1) competitive landscape: 5 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Angiotensin II receptor blocker + thiazide diuretic combination. Area: Cardiovascular.

phase 3 Angiotensin II receptor blocker + thiazide diuretic combination AT1 receptor (angiotensin II type 1 receptor); sodium-chloride cotransporter Cardiovascular Small molecule Live · refreshed every 30 min

Target snapshot

Candesartan+HCTZ - Phase 1 (Candesartan+HCTZ - Phase 1) — Novartis. Candesartan blocks angiotensin II receptors to lower blood pressure, while HCTZ is a thiazide diuretic that reduces fluid volume and sodium reabsorption.

Comparator set (5 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Candesartan+HCTZ - Phase 1 TARGET Candesartan+HCTZ - Phase 1 Novartis phase 3 Angiotensin II receptor blocker + thiazide diuretic combination AT1 receptor (angiotensin II type 1 receptor); sodium-chloride cotransporter
olmesartan medoxomil + hydrochlorothiazide, if necessary olmesartan medoxomil + hydrochlorothiazide, if necessary Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company marketed Angiotensin II receptor blocker + thiazide diuretic combination AT1 receptor (angiotensin II type 1 receptor); sodium-chloride cotransporter
Micardis plus 80/12.5 Micardis plus 80/12.5 Heart Care Foundation marketed Angiotensin II receptor blocker + thiazide diuretic combination AT1 receptor (angiotensin II type 1 receptor); thiazide-sensitive sodium-chloride cotransporter
losartan and HCTZ losartan and HCTZ InVasc Therapeutics, Inc. marketed Angiotensin II receptor blocker + thiazide diuretic combination AT1 receptor (losartan); sodium-chloride cotransporter (HCTZ)
Candesartan plus Hydrochlorothiazide Candesartan plus Hydrochlorothiazide Novartis phase 3 Angiotensin II receptor blocker + Thiazide diuretic combination AT1 receptor (angiotensin II type 1 receptor); sodium-chloride cotransporter
Fimasartan; Hydrochlorothiazide Fimasartan; Hydrochlorothiazide Stendhal Americas, S.A. phase 3 Angiotensin II receptor blocker + thiazide diuretic combination AT1 receptor (fimasartan); sodium-chloride cotransporter (hydrochlorothiazide)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Angiotensin II receptor blocker + thiazide diuretic combination class)

  1. Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company · 1 drug in this class
  2. Heart Care Foundation · 1 drug in this class
  3. InVasc Therapeutics, Inc. · 1 drug in this class
  4. Novartis · 1 drug in this class
  5. Stendhal Americas, S.A. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Candesartan+HCTZ - Phase 1 — Competitive Intelligence Brief. https://druglandscape.com/ci/candesartan-hctz-phase-1. Accessed 2026-05-16.

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