Who are calcipotriene + clobetasol propionate's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Calcipotriene and betamethasone dipropionate ointment, Calcipotriene/betamethasone gel and ointment, LEO 90105 = calcipotriol + betamethasone dipropionate, Daivobet® gel.

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Last reviewed 2026-05-17 · How we verify

calcipotriene + clobetasol propionate — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

calcipotriene + clobetasol propionate (calcipotriene + clobetasol propionate) competitive landscape: 4 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Topical combination therapy (vitamin D analog + corticosteroid). Area: Dermatology.

marketed Topical combination therapy (vitamin D analog + corticosteroid) Vitamin D receptor (VDR) and glucocorticoid receptor (GR) Dermatology Small molecule Live · refreshed every 30 min

Target snapshot

calcipotriene + clobetasol propionate (calcipotriene + clobetasol propionate) — Leon Kircik, M.D.. Calcipotriene is a vitamin D analog that regulates skin cell differentiation and proliferation, while clobetasol propionate is a potent corticosteroid that suppresses inflammation and immune response in the skin.

Comparator set (4 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
calcipotriene + clobetasol propionate TARGET	calcipotriene + clobetasol propionate	Leon Kircik, M.D.	marketed	Topical combination therapy (vitamin D analog + corticosteroid)	Vitamin D receptor (VDR) and glucocorticoid receptor (GR)
Calcipotriene and betamethasone dipropionate ointment	Calcipotriene and betamethasone dipropionate ointment	Galderma R&D	marketed	Topical combination therapy (vitamin D analog + corticosteroid)	Vitamin D receptor (VDR) and glucocorticoid receptor (GR)
Calcipotriene/betamethasone gel and ointment	Calcipotriene/betamethasone gel and ointment	LEO Pharma	phase 3	Topical combination therapy (vitamin D analog + corticosteroid)	Vitamin D receptor (VDR); glucocorticoid receptor (GR)
LEO 90105 = calcipotriol + betamethasone dipropionate	LEO 90105 = calcipotriol + betamethasone dipropionate	LEO Pharma	phase 3	Topical combination therapy (vitamin D analog + corticosteroid)	Vitamin D receptor (VDR); glucocorticoid receptor (GR)
Daivobet® gel	Daivobet® gel	LEO Pharma	phase 3	Topical combination therapy (vitamin D analog + corticosteroid)	Vitamin D receptor (VDR); glucocorticoid receptor (GR)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Topical combination therapy (vitamin D analog + corticosteroid) class)

LEO Pharma · 3 drugs in this class
Galderma R&D · 1 drug in this class
Leon Kircik, M.D. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). calcipotriene + clobetasol propionate — Competitive Intelligence Brief. https://druglandscape.com/ci/calcipotriene-clobetasol-propionate. Accessed 2026-05-17.

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