Who are Calcipotriene/betamethasone gel and ointment's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): calcipotriene + clobetasol propionate, Calcipotriene and betamethasone dipropionate ointment, Daivobet® gel, LEO 90105 = calcipotriol + betamethasone dipropionate.

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Last reviewed 2026-05-17 · How we verify

Calcipotriene/betamethasone gel and ointment — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Calcipotriene/betamethasone gel and ointment (Calcipotriene/betamethasone gel and ointment) competitive landscape: 4 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Topical combination therapy (vitamin D analog + corticosteroid). Area: Dermatology.

phase 3 Topical combination therapy (vitamin D analog + corticosteroid) Vitamin D receptor (VDR); glucocorticoid receptor (GR) Dermatology Small molecule Live · refreshed every 30 min

Target snapshot

Calcipotriene/betamethasone gel and ointment (Calcipotriene/betamethasone gel and ointment) — LEO Pharma. Calcipotriene (a vitamin D analog) reduces skin cell proliferation and promotes differentiation, while betamethasone (a corticosteroid) suppresses inflammation and immune response in psoriatic skin.

Comparator set (4 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Calcipotriene/betamethasone gel and ointment TARGET	Calcipotriene/betamethasone gel and ointment	LEO Pharma	phase 3	Topical combination therapy (vitamin D analog + corticosteroid)	Vitamin D receptor (VDR); glucocorticoid receptor (GR)
calcipotriene + clobetasol propionate	calcipotriene + clobetasol propionate	Leon Kircik, M.D.	marketed	Topical combination therapy (vitamin D analog + corticosteroid)	Vitamin D receptor (VDR) and glucocorticoid receptor (GR)
Calcipotriene and betamethasone dipropionate ointment	Calcipotriene and betamethasone dipropionate ointment	Galderma R&D	marketed	Topical combination therapy (vitamin D analog + corticosteroid)	Vitamin D receptor (VDR) and glucocorticoid receptor (GR)
Daivobet® gel	Daivobet® gel	LEO Pharma	phase 3	Topical combination therapy (vitamin D analog + corticosteroid)	Vitamin D receptor (VDR); glucocorticoid receptor (GR)
LEO 90105 = calcipotriol + betamethasone dipropionate	LEO 90105 = calcipotriol + betamethasone dipropionate	LEO Pharma	phase 3	Topical combination therapy (vitamin D analog + corticosteroid)	Vitamin D receptor (VDR); glucocorticoid receptor (GR)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Topical combination therapy (vitamin D analog + corticosteroid) class)

LEO Pharma · 3 drugs in this class
Galderma R&D · 1 drug in this class
Leon Kircik, M.D. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Calcipotriene/betamethasone gel and ointment — Competitive Intelligence Brief. https://druglandscape.com/ci/calcipotriene-betamethasone-gel-and-ointment. Accessed 2026-05-17.

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