Who are C5 Inhibitor's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Izervay, AVACINCAPTAD PEGOL SODIUM, Veopoz, Tavneos, Ultomiris, H5G1.1.

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Last reviewed 2026-06-09 · How we verify

C5 Inhibitor — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

C5 Inhibitor (C5 Inhibitor) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Complement C5 inhibitor. Area: Immunology.

phase 3 Complement C5 inhibitor C5 Immunology Small molecule Live · refreshed every 30 min

Target snapshot

C5 Inhibitor (C5 Inhibitor) — Alexion Pharmaceuticals, Inc.. A C5 complement inhibitor blocks the activation of the C5 component of the complement cascade, preventing formation of the membrane attack complex and reducing inflammatory cell activation.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
C5 Inhibitor TARGET	C5 Inhibitor	Alexion Pharmaceuticals, Inc.	phase 3	Complement C5 inhibitor	C5
Izervay	AVACINCAPTAD PEGOL	Astellas Pharma	marketed		Complement C5	2023-01-01
AVACINCAPTAD PEGOL SODIUM	AVACINCAPTAD PEGOL SODIUM		marketed	Complement Inhibitors	Complement C5	2023-01-01
Veopoz	POZELIMAB	Regeneron	marketed	Complement Inhibitor [EPC]	Complement C5	2023-01-01
Tavneos	AVACOPAN	Chemocentryx	marketed	Complement 5a Receptor Antagonist [EPC]	C5a anaphylatoxin chemotactic receptor 1	2021-01-01
Ultomiris	RAVULIZUMAB	AstraZeneca	marketed	Complement Inhibitor [EPC]	Complement C5	2018-01-01
H5G1.1	ECULIZUMAB	AstraZeneca	marketed	Complement Inhibitor [EPC]	C5	2007-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2026-11-11 — AVACINCAPTAD PEGOL SODIUM · 8236773 · Method of Use · US
2027-02-14 — AVACINCAPTAD PEGOL SODIUM · 9617546 · Compound · US
2027-02-14 — AVACINCAPTAD PEGOL SODIUM · 7579456 · Compound · US
2034-07-11 — AVACINCAPTAD PEGOL SODIUM · 11491176 · Method of Use · US
2034-07-11 — AVACINCAPTAD PEGOL SODIUM · 11273171 · Method of Use · US
2034-07-11 — AVACINCAPTAD PEGOL SODIUM · 12016875 · Method of Use · US

Sponsor landscape (Complement C5 inhibitor class)

Alexion Pharmaceuticals, Inc. · 1 drug in this class
Bausch & Lomb Incorporated · 1 drug in this class
Massachusetts General Hospital · 1 drug in this class
University Hospital, Tours · 1 drug in this class
Wuhan Createrna Science and Technology Co., Ltd · 1 drug in this class

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Cite this brief

Drug Landscape (2026). C5 Inhibitor — Competitive Intelligence Brief. https://druglandscape.com/ci/c5-inhibitor. Accessed 2026-06-09.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing