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C=Inhaled Alprazolam 1 m — Competitive Intelligence Brief
phase 2
benzodiazepine
GABAA receptor
Neurology
Small molecule
Live · refreshed every 30 min
Target snapshot
C=Inhaled Alprazolam 1 m (C=Inhaled Alprazolam 1 m) — Alexza Pharmaceuticals, Inc.. Alprazolam acts as a positive allosteric modulator of the GABAA receptor, enhancing the inhibitory effects of GABA in the central nervous system.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| C=Inhaled Alprazolam 1 m TARGET | C=Inhaled Alprazolam 1 m | Alexza Pharmaceuticals, Inc. | phase 2 | benzodiazepine | GABAA receptor | |
| Onfi | CLOBAZAM | Lundbeck Pharms Llc | marketed | Benzodiazepine [EPC] | GABA-A receptor alpha-1/beta-2/gamma-2 | 2011-01-01 |
| Romazicon | FLUMAZENIL | marketed | Benzodiazepine Antagonist [EPC] | Gamma-aminobutyric acid receptor subunit alpha-5 | 1991-01-01 | |
| Prosom | ESTAZOLAM | Abbott | marketed | Benzodiazepine [EPC] | GABA-A receptor alpha-1/beta-2/gamma-2 | 1990-01-01 |
| Versed | midazolam | Generic (originally Roche) | marketed | Benzodiazepine (short-acting) | Multidrug resistance protein 1, Cytochrome P450 3A4, GABA A receptor alpha-3/beta-2/gamma-2 | 1985-12-20 |
| Versed | Midazolam Hydrochloride | Takeda Pharmaceutical Company Limited | marketed | Benzodiazepine | GABA A receptor alpha-5/beta-2/gamma-2 | 1985-01-01 |
| Xanax | alprazolam | Generic (originally Upjohn/Pfizer) | marketed | Benzodiazepine (triazolobenzodiazepine) | Bromodomain-containing protein 4, Platelet-activating factor receptor, Cytochrome P450 3A4 | 1981-10-16 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
- — Versed · 9687495 · Formulation · US
- — Versed · 9289432 · Formulation · US
- — Versed · 8217033 · Formulation · US
- — Versed · 8809322 · Formulation · US
- — Versed · 9687495 · Formulation · US
- — Versed · 9289432 · Formulation · US
- — Versed · 8217033 · Formulation · US
- — Versed · 8809322 · Formulation · US
- — Versed · 10966990 · Formulation · US
- — Versed · 10966990 · Formulation · US
- — Onfi · 12403090 · Formulation · US
- — Onfi · 12290597 · Formulation · US
- — Onfi · 11541002 · Formulation · US
Sponsor landscape (benzodiazepine class)
- Alexza Pharmaceuticals, Inc. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). C=Inhaled Alprazolam 1 m — Competitive Intelligence Brief. https://druglandscape.com/ci/c-inhaled-alprazolam-1-m. Accessed 2026-05-17.
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