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Ambuphylline — Competitive Intelligence Brief

Ambuphylline (bufylline) competitive landscape: 3 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: bufylline. Area: Cardiovascular.

unknown bufylline Adenosine receptor A3, Alkaline phosphatase, tissue-nonspecific isozyme, Adenosine receptor A1 Cardiovascular Live · refreshed every 30 min

Target snapshot

Ambuphylline (bufylline). Ambuphylline works by blocking the adenosine receptor A1, which helps to increase heart rate and blood pressure.

Comparator set (3 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Ambuphylline TARGET bufylline unknown bufylline Adenosine receptor A3, Alkaline phosphatase, tissue-nonspecific isozyme, Adenosine receptor A1
Oxtriphylline choline theophyllinate Warner Chilcott Llc marketed choline theophyllinate Adenosine receptor A3, Alkaline phosphatase, tissue-nonspecific isozyme, Adenosine receptor A1 1981-01-01
Aminophyllin Aminophyllin University of Padova marketed Adenosine receptor A3, Alkaline phosphatase, tissue-nonspecific isozyme, Adenosine receptor A1
Theophyllin Theophyllin University of Bergen marketed Adenosine receptor A3, Alkaline phosphatase, tissue-nonspecific isozyme, Adenosine receptor A1

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (bufylline class)

  1. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Ambuphylline — Competitive Intelligence Brief. https://druglandscape.com/ci/bufylline. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing