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Botulinum Toxin A - Open Label — Competitive Intelligence Brief
phase 3
Neurotoxin; Acetylcholine release inhibitor
SNAP-25 (synaptosome-associated protein of 25 kDa)
Neurology; Aesthetics; Pain Management
Small molecule
Live · refreshed every 30 min
Target snapshot
Botulinum Toxin A - Open Label (Botulinum Toxin A - Open Label) — Croma-Pharma GmbH. Botulinum Toxin A blocks acetylcholine release at the neuromuscular junction by cleaving SNARE proteins, causing temporary muscle paralysis.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Botulinum Toxin A - Open Label TARGET | Botulinum Toxin A - Open Label | Croma-Pharma GmbH | phase 3 | Neurotoxin; Acetylcholine release inhibitor | SNAP-25 (synaptosome-associated protein of 25 kDa) | |
| Nuceiva | BOTULINUM TOXIN TYPE A | GlaxoSmithKline K.K. | marketed | Acetylcholine Release Inhibitor [EPC] | Synaptosomal-associated protein 25 | 2019-01-01 |
| Xeomin | INCOBOTULINUMTOXINA | Merz Pharms | marketed | Acetylcholine Release Inhibitor [EPC] | 2015-01-01 | |
| Botox | ONABOTULINUMTOXINA | Allergan | marketed | Acetylcholine Release Inhibitor [EPC] | SNAP-25 | 2010-01-01 |
| Myobloc | RIMABOTULINUMTOXINB | Elan Pharm | marketed | Acetylcholine Release Inhibitor [EPC] | 2009-01-01 | |
| Botulinum toxin A 150u | Botulinum toxin A 150u | EvergreenHealth | marketed | Neurotoxin; Acetylcholine release inhibitor | SNARE proteins (specifically SNAP-25) | |
| DAXXIFY | DAXIBOTULINUMTOXINA-LANM | REVANCE THERAPEUTICS, INC. | marketed | Acetylcholine Release Inhibitor [EPC] |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Neurotoxin; Acetylcholine release inhibitor class)
- EvergreenHealth · 2 drugs in this class
- Croma-Pharma GmbH · 1 drug in this class
- Helse Nord-Trøndelag HF · 1 drug in this class
- NICHD Pelvic Floor Disorders Network · 1 drug in this class
- Universidad Autonoma de Nuevo Leon · 1 drug in this class
- University of Calgary · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Botulinum Toxin A - Open Label — Competitive Intelligence Brief. https://druglandscape.com/ci/botulinum-toxin-a-open-label. Accessed 2026-05-16.
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