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BF-200 ALA 1% — Competitive Intelligence Brief
phase 2
photosensitizer
protoporphyrin IX (PpIX)
Dermatology
Small molecule
Live · refreshed every 30 min
Target snapshot
BF-200 ALA 1% (BF-200 ALA 1%) — Biofrontera Bioscience GmbH. BF-200 ALA 1% is a topical photosensitizer that, when activated by light, generates reactive oxygen species to induce cell death in targeted tissues.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| BF-200 ALA 1% TARGET | BF-200 ALA 1% | Biofrontera Bioscience GmbH | phase 2 | photosensitizer | protoporphyrin IX (PpIX) | |
| Rose Bengal | Rose Bengal | University of California, San Francisco | marketed | Photosensitizer | ||
| aminolevulinic acid (ALA) | aminolevulinic acid (ALA) | University of California, Davis | marketed | Photosensitizer | Protoporphyrin IX (endogenous photosensitizer generated from ALA) | |
| Hemoporfin PDT | Hemoporfin PDT | Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. | marketed | Photosensitizer | Porphyrin-based photosensitizer (non-receptor mediated) | |
| 5-Methoxypsoralen | 5-Methoxypsoralen | Medical University of Vienna | phase 3 | Furocoumarin photosensitizer | DNA (intercalating agent) | |
| padeliporfin VTP | padeliporfin VTP | Steba Biotech S.A. | phase 3 | Photosensitizer | ||
| verteporfin, bevacizumab, triamcinolone acetonide | verteporfin, bevacizumab, triamcinolone acetonide | Shahid Beheshti University of Medical Sciences | phase 3 | photosensitizer, monoclonal antibody, corticosteroid | VEGF-A, VEGF receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (photosensitizer class)
- Biofrontera Bioscience GmbH · 1 drug in this class
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Cite this brief
Drug Landscape (2026). BF-200 ALA 1% — Competitive Intelligence Brief. https://druglandscape.com/ci/bf-200-ala-1. Accessed 2026-06-10.
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