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BF-200 ALA 1% — Competitive Intelligence Brief

BF-200 ALA 1% (BF-200 ALA 1%) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: photosensitizer. Area: Dermatology.

phase 2 photosensitizer protoporphyrin IX (PpIX) Dermatology Small molecule Live · refreshed every 30 min

Target snapshot

BF-200 ALA 1% (BF-200 ALA 1%) — Biofrontera Bioscience GmbH. BF-200 ALA 1% is a topical photosensitizer that, when activated by light, generates reactive oxygen species to induce cell death in targeted tissues.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
BF-200 ALA 1% TARGET BF-200 ALA 1% Biofrontera Bioscience GmbH phase 2 photosensitizer protoporphyrin IX (PpIX)
Rose Bengal Rose Bengal University of California, San Francisco marketed Photosensitizer
aminolevulinic acid (ALA) aminolevulinic acid (ALA) University of California, Davis marketed Photosensitizer Protoporphyrin IX (endogenous photosensitizer generated from ALA)
Hemoporfin PDT Hemoporfin PDT Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. marketed Photosensitizer Porphyrin-based photosensitizer (non-receptor mediated)
5-Methoxypsoralen 5-Methoxypsoralen Medical University of Vienna phase 3 Furocoumarin photosensitizer DNA (intercalating agent)
padeliporfin VTP padeliporfin VTP Steba Biotech S.A. phase 3 Photosensitizer
verteporfin, bevacizumab, triamcinolone acetonide verteporfin, bevacizumab, triamcinolone acetonide Shahid Beheshti University of Medical Sciences phase 3 photosensitizer, monoclonal antibody, corticosteroid VEGF-A, VEGF receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (photosensitizer class)

  1. Biofrontera Bioscience GmbH · 1 drug in this class

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Cite this brief

Drug Landscape (2026). BF-200 ALA 1% — Competitive Intelligence Brief. https://druglandscape.com/ci/bf-200-ala-1. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing