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Besifovir dipivoxil — Competitive Intelligence Brief
marketed
Nucleotide reverse transcriptase inhibitor
Hepatitis B virus reverse transcriptase
Virology / Hepatology
Small molecule
Live · refreshed every 30 min
Target snapshot
Besifovir dipivoxil (Besifovir dipivoxil) — IlDong Pharmaceutical Co Ltd. Besifovir dipivoxil is a nucleotide reverse transcriptase inhibitor that blocks hepatitis B virus replication by inhibiting the viral reverse transcriptase enzyme.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Besifovir dipivoxil TARGET | Besifovir dipivoxil | IlDong Pharmaceutical Co Ltd | marketed | Nucleotide reverse transcriptase inhibitor | Hepatitis B virus reverse transcriptase | |
| NAs+IFN-α | NAs+IFN-α | Beijing 302 Hospital | marketed | Antiviral combination therapy | Hepatitis B virus reverse transcriptase; interferon-alpha receptor signaling | |
| Telbivudine treatment | Telbivudine treatment | Southeast University, China | marketed | Nucleoside reverse transcriptase inhibitor (NRTI) | Hepatitis B virus reverse transcriptase | |
| Tacrolimus &entecavir | Tacrolimus &entecavir | Guangdong Provincial People's Hospital | marketed | Combination immunosuppressant and antiviral | Calcineurin (tacrolimus); Hepatitis B virus reverse transcriptase (entecavir) | |
| Telbivudine (Standard of Care) | Telbivudine (Standard of Care) | Nanfang Hospital, Southern Medical University | marketed | Nucleoside reverse transcriptase inhibitor (NRTI) | Hepatitis B virus reverse transcriptase | |
| Telbivudine, Lamivudine, Adefovir ,Enecavir | Telbivudine, Lamivudine, Adefovir ,Enecavir | Shao-quan Zhang | marketed | Nucleoside/nucleotide reverse transcriptase inhibitor (NRTI/NtRTI) | Hepatitis B virus reverse transcriptase | |
| Blank maleate entecavir tablets | Blank maleate entecavir tablets | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | marketed | Nucleoside reverse transcriptase inhibitor | Hepatitis B virus reverse transcriptase |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Nucleotide reverse transcriptase inhibitor class)
- GlaxoSmithKline · 2 drugs in this class
- IlDong Pharmaceutical Co Ltd · 1 drug in this class
- Bristol-Myers Squibb · 1 drug in this class
- Merck Sharp & Dohme LLC · 1 drug in this class
- National Institute of Allergy and Infectious Diseases (NIAID) · 1 drug in this class
- Sun Yat-sen University · 1 drug in this class
- Jiangxi Kvvit Pharmaceutical Co., Ltd. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Besifovir dipivoxil — Competitive Intelligence Brief. https://druglandscape.com/ci/besifovir-dipivoxil. Accessed 2026-05-18.
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