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B arm (DAC) — Competitive Intelligence Brief

B arm (DAC) (B arm (DAC)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Combination chemotherapy regimen. Area: Oncology.

phase 3 Combination chemotherapy regimen Oncology Small molecule Live · refreshed every 30 min

Target snapshot

B arm (DAC) (B arm (DAC)) — Polish Adult Leukemia Group. DAC (daunorubicin, cytarabine, and cladribine) is a combination chemotherapy regimen that damages leukemic cell DNA and inhibits nucleotide synthesis to induce apoptosis.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
B arm (DAC) TARGET B arm (DAC) Polish Adult Leukemia Group phase 3 Combination chemotherapy regimen
Carboplatin, Etoposide, Ifosfamide Carboplatin, Etoposide, Ifosfamide University Hospital Muenster marketed Combination chemotherapy regimen DNA (multiple mechanisms: alkylation, cross-linking, topoisomerase II inhibition)
CEV chemotherapy CEV chemotherapy Sun Yat-sen University marketed Combination chemotherapy regimen
SOX Chemotherapy SOX Chemotherapy The First Affiliated Hospital with Nanjing Medical University marketed Combination chemotherapy regimen
Dexamethasona, Idarubicine, ARA-C, Methotrexate Dexamethasona, Idarubicine, ARA-C, Methotrexate PETHEMA Foundation marketed Combination chemotherapy regimen
PTH followed by dose dense AC of FEC PTH followed by dose dense AC of FEC Agendia marketed Combination chemotherapy regimen with monoclonal antibody HER2 receptor; microtubule; DNA (topoisomerase II)
CVP CVP SCRI Development Innovations, LLC marketed Combination chemotherapy regimen

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Combination chemotherapy regimen class)

  1. Sun Yat-sen University · 5 drugs in this class
  2. Sixth Affiliated Hospital, Sun Yat-sen University · 2 drugs in this class
  3. Hoffmann-La Roche · 2 drugs in this class
  4. University Hospital, Bordeaux · 2 drugs in this class
  5. Beijing Friendship Hospital · 1 drug in this class
  6. Centre Hospitalier Universitaire Dijon · 1 drug in this class
  7. Amgen · 1 drug in this class
  8. Chungnam National University Hospital · 1 drug in this class
  9. AstraZeneca · 1 drug in this class
  10. Children's Cancer Group, China · 1 drug in this class

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Cite this brief

Drug Landscape (2026). B arm (DAC) — Competitive Intelligence Brief. https://druglandscape.com/ci/b-arm-dac. Accessed 2026-05-13.

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