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B arm (DAC) — Competitive Intelligence Brief
phase 3
Combination chemotherapy regimen
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
B arm (DAC) (B arm (DAC)) — Polish Adult Leukemia Group. DAC (daunorubicin, cytarabine, and cladribine) is a combination chemotherapy regimen that damages leukemic cell DNA and inhibits nucleotide synthesis to induce apoptosis.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| B arm (DAC) TARGET | B arm (DAC) | Polish Adult Leukemia Group | phase 3 | Combination chemotherapy regimen | ||
| Carboplatin, Etoposide, Ifosfamide | Carboplatin, Etoposide, Ifosfamide | University Hospital Muenster | marketed | Combination chemotherapy regimen | DNA (multiple mechanisms: alkylation, cross-linking, topoisomerase II inhibition) | |
| CEV chemotherapy | CEV chemotherapy | Sun Yat-sen University | marketed | Combination chemotherapy regimen | ||
| SOX Chemotherapy | SOX Chemotherapy | The First Affiliated Hospital with Nanjing Medical University | marketed | Combination chemotherapy regimen | ||
| Dexamethasona, Idarubicine, ARA-C, Methotrexate | Dexamethasona, Idarubicine, ARA-C, Methotrexate | PETHEMA Foundation | marketed | Combination chemotherapy regimen | ||
| PTH followed by dose dense AC of FEC | PTH followed by dose dense AC of FEC | Agendia | marketed | Combination chemotherapy regimen with monoclonal antibody | HER2 receptor; microtubule; DNA (topoisomerase II) | |
| CVP | CVP | SCRI Development Innovations, LLC | marketed | Combination chemotherapy regimen |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Combination chemotherapy regimen class)
- Sun Yat-sen University · 5 drugs in this class
- Sixth Affiliated Hospital, Sun Yat-sen University · 2 drugs in this class
- Hoffmann-La Roche · 2 drugs in this class
- University Hospital, Bordeaux · 2 drugs in this class
- Beijing Friendship Hospital · 1 drug in this class
- Centre Hospitalier Universitaire Dijon · 1 drug in this class
- Amgen · 1 drug in this class
- Chungnam National University Hospital · 1 drug in this class
- AstraZeneca · 1 drug in this class
- Children's Cancer Group, China · 1 drug in this class
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Cite this brief
Drug Landscape (2026). B arm (DAC) — Competitive Intelligence Brief. https://druglandscape.com/ci/b-arm-dac. Accessed 2026-05-13.
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