Who are AZD2281's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Talazoparib with enzalutamide, Talzenna, NIRAPARIB, Rubraca, Lynparza, Talzenna.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-14 · How we verify

AZD2281 — Competitive Intelligence Brief

AZD2281 (AZD2281) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: PARP inhibitor. Area: Oncology.

phase 2 PARP inhibitor PARP Oncology Small molecule Live · refreshed every 30 min

Target snapshot

AZD2281 (AZD2281) — AstraZeneca. PARP inhibitor

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
AZD2281 TARGET	AZD2281	AstraZeneca	phase 2	PARP inhibitor	PARP
Talazoparib with enzalutamide	talazoparib-with-enzalutamide	Pfizer	marketed	PARP inhibitor and androgen receptor inhibitor	PARP enzymes and androgen receptor	Not yet launched
Talzenna	talazoparib-tosylate	Pfizer	marketed	Poly(ADP-Ribose) Polymerase Inhibitor	PARP1, PARP2	2018-01-01
NIRAPARIB	NIRAPARIB		marketed		PARP-1, PARP-2, CYP17	2017-01-01
Rubraca	RUCAPARIB	Pfizer	marketed		PARP-1, PARP-2, PARP-3	2016-01-01
Lynparza	Lynparza	University of Texas Southwestern Medical Center	marketed		Mono [ADP-ribose] polymerase PARP16, Tankyrase-1, Tankyrase-2
Talzenna	Talazoparib Tosylate	Pfizer Inc.	marketed	PARP inhibitor	PARP1 and PARP2 enzymes

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2029-07-27 — Talzenna · 8420650 · US
2029-07-27 — Talzenna · 9820985 · US
2029-07-27 — Talzenna · 10780088 · US
2029-10-19 — Talzenna · 8012976 · US
2031-10-20 — Talzenna · 8735392 · US
2031-10-20 — Talzenna · 10189837 · US

Sponsor landscape (PARP inhibitor class)

AstraZeneca · 5 drugs in this class
BeiGene · 2 drugs in this class
Clovis Oncology, Inc. · 1 drug in this class
Fondazione Ricerca Traslazionale · 1 drug in this class
GERCOR - Multidisciplinary Oncology Cooperative Group · 1 drug in this class
Hospices Civils de Lyon · 1 drug in this class
Pfizer Inc. · 1 drug in this class
Sanofi · 1 drug in this class
Tesaro, Inc. · 1 drug in this class
The First Affiliated Hospital of Xiamen University · 1 drug in this class

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Cite this brief

Drug Landscape (2026). AZD2281 — Competitive Intelligence Brief. https://druglandscape.com/ci/azd2281. Accessed 2026-05-14.

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