Last reviewed · How we verify

Atrasentan low dose group — Competitive Intelligence Brief

Atrasentan low dose group (Atrasentan low dose group) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Endothelin receptor antagonist. Area: Cardiovascular.

phase 2 Endothelin receptor antagonist Endothelin receptor Cardiovascular Small molecule Live · refreshed every 30 min

Target snapshot

Atrasentan low dose group (Atrasentan low dose group) — AbbVie (prior sponsor, Abbott). Endothelin receptor antagonist

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Atrasentan low dose group TARGET Atrasentan low dose group AbbVie (prior sponsor, Abbott) phase 2 Endothelin receptor antagonist Endothelin receptor
"Nefecon®","Ambrisentan" "Nefecon®","Ambrisentan" The First Hospital of Jilin University marketed Endothelin receptor antagonist (ERA) Endothelin receptor type A (ETA)
Tracleer® Tracleer® Actelion marketed Endothelin receptor antagonist Endothelin receptor A (ETA) and Endothelin receptor B (ETB)
ERA as specific PAH treatment ERA as specific PAH treatment Eli Lilly and Company phase 3 Endothelin receptor antagonist Endothelin receptor (ETA/ETB)
EFI/ACT-385781A EFI/ACT-385781A Actelion phase 3 Selective endothelin receptor antagonist Endothelin receptor (ETA/ETB)
Macitentan/Tadalafil FDC Macitentan/Tadalafil FDC Actelion phase 3 Endothelin receptor antagonist / Phosphodiesterase-5 inhibitor combination Endothelin receptor A and B / Phosphodiesterase-5
Bosentan and Sildenafil Bosentan and Sildenafil Rigshospitalet, Denmark phase 3 Endothelin receptor antagonist and phosphodiesterase-5 inhibitor combination Endothelin receptors (ETA/ETB) and phosphodiesterase-5

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Endothelin receptor antagonist class)

  1. AbbVie (prior sponsor, Abbott) · 2 drugs in this class
  2. Actelion · 2 drugs in this class
  3. Bayer · 1 drug in this class
  4. Dr Sudarshan Rajagopal · 1 drug in this class
  5. Eli Lilly and Company · 1 drug in this class
  6. Elpen Pharmaceutical Co. Inc. · 1 drug in this class
  7. National Heart, Lung, and Blood Institute (NHLBI) · 1 drug in this class

Subscribe to ongoing alerts

Push every new event for this competitive set into your RSS reader, IFTTT/Zapier workflow, or email digest:

Cite this brief

Drug Landscape (2026). Atrasentan low dose group — Competitive Intelligence Brief. https://druglandscape.com/ci/atrasentan-low-dose-group. Accessed 2026-05-16.

Build your own brief

Pick any drug + add comparators: