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Atrasentan low dose group — Competitive Intelligence Brief
phase 2
Endothelin receptor antagonist
Endothelin receptor
Cardiovascular
Small molecule
Live · refreshed every 30 min
Target snapshot
Atrasentan low dose group (Atrasentan low dose group) — AbbVie (prior sponsor, Abbott). Endothelin receptor antagonist
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Atrasentan low dose group TARGET | Atrasentan low dose group | AbbVie (prior sponsor, Abbott) | phase 2 | Endothelin receptor antagonist | Endothelin receptor | |
| "Nefecon®","Ambrisentan" | "Nefecon®","Ambrisentan" | The First Hospital of Jilin University | marketed | Endothelin receptor antagonist (ERA) | Endothelin receptor type A (ETA) | |
| Tracleer® | Tracleer® | Actelion | marketed | Endothelin receptor antagonist | Endothelin receptor A (ETA) and Endothelin receptor B (ETB) | |
| ERA as specific PAH treatment | ERA as specific PAH treatment | Eli Lilly and Company | phase 3 | Endothelin receptor antagonist | Endothelin receptor (ETA/ETB) | |
| EFI/ACT-385781A | EFI/ACT-385781A | Actelion | phase 3 | Selective endothelin receptor antagonist | Endothelin receptor (ETA/ETB) | |
| Macitentan/Tadalafil FDC | Macitentan/Tadalafil FDC | Actelion | phase 3 | Endothelin receptor antagonist / Phosphodiesterase-5 inhibitor combination | Endothelin receptor A and B / Phosphodiesterase-5 | |
| Bosentan and Sildenafil | Bosentan and Sildenafil | Rigshospitalet, Denmark | phase 3 | Endothelin receptor antagonist and phosphodiesterase-5 inhibitor combination | Endothelin receptors (ETA/ETB) and phosphodiesterase-5 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Endothelin receptor antagonist class)
- AbbVie (prior sponsor, Abbott) · 2 drugs in this class
- Actelion · 2 drugs in this class
- Bayer · 1 drug in this class
- Dr Sudarshan Rajagopal · 1 drug in this class
- Eli Lilly and Company · 1 drug in this class
- Elpen Pharmaceutical Co. Inc. · 1 drug in this class
- National Heart, Lung, and Blood Institute (NHLBI) · 1 drug in this class
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- Atrasentan low dose group CI watch — RSS
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Cite this brief
Drug Landscape (2026). Atrasentan low dose group — Competitive Intelligence Brief. https://druglandscape.com/ci/atrasentan-low-dose-group. Accessed 2026-05-16.
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