Who are ATRA's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Sohonos, TRIFAROTENE, Panretin, Targretin, Differin, Soriatane.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

How do I get this as a recurring report?

Subscribe to /feed/ci/atra.xml in any RSS reader (Feedly, Inoreader, NewsBlur). Every regulatory action, trial readout, or patent event lands in your feed automatically.

Last reviewed 2026-05-14 · How we verify

ATRA — Competitive Intelligence Brief

ATRA (ATRA) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Retinoid; differentiation agent. Area: Oncology.

marketed Retinoid; differentiation agent Retinoic acid receptor (RAR), particularly RAR-alpha Oncology Small molecule Live · refreshed every 30 min

Target snapshot

ATRA (ATRA) — South China Children's Leukemia Group. ATRA (all-trans retinoic acid) promotes differentiation of acute promyelocytic leukemia cells and induces apoptosis by binding to retinoic acid receptors.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
ATRA TARGET	ATRA	South China Children's Leukemia Group	marketed	Retinoid; differentiation agent	Retinoic acid receptor (RAR), particularly RAR-alpha
Sohonos	PALOVAROTENE	Ipsen	marketed	Retinoid [EPC]	Retinoic acid receptor gamma	2023-01-01
TRIFAROTENE	TRIFAROTENE		marketed	Retinoid [EPC]		2019-01-01
Panretin	ALITRETINOIN	Advanz	marketed	Retinoid [EPC]	Retinoic acid receptor beta	1999-01-01
Targretin	BEXAROTENE	Bausch Health	marketed	Retinoid [EPC]	Retinoic acid receptor RXR-beta	1999-01-01
Differin	ADAPALENE	Galderma Labs Lp	marketed	Retinoid [EPC]	Retinoic acid receptor beta	1996-01-01
Soriatane	ACITRETIN	Stiefel Labs Inc	marketed	Retinoid [EPC]	Bile salt export pump	1996-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2026-09-15 — Differin · 8435502 · Formulation · US
2026-09-15 — Differin · 8709392 · Formulation · US
2028-05-31 — Differin · 7998467 · Formulation · US

Sponsor landscape (Retinoid; differentiation agent class)

Groupe d'etude et de travail sur les leucemies aigues promyelocytaires · 1 drug in this class
Mahmoud Ramadan mohamed Elkazzaz · 1 drug in this class
South China Children's Leukemia Group · 1 drug in this class

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Cite this brief

Drug Landscape (2026). ATRA — Competitive Intelligence Brief. https://druglandscape.com/ci/atra. Accessed 2026-05-14.

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