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ATB-346 mid-dose — Competitive Intelligence Brief
phase 2
NSAID
COX-2
Pain
Small molecule
Live · refreshed every 30 min
Target snapshot
ATB-346 mid-dose (ATB-346 mid-dose) — Antibe Therapeutics Inc.. ATB-346 mid-dose is a nonsteroidal anti-inflammatory drug (NSAID) that selectively targets COX-2 to reduce gastrointestinal toxicity.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| ATB-346 mid-dose TARGET | ATB-346 mid-dose | Antibe Therapeutics Inc. | phase 2 | NSAID | COX-2 | |
| Celebrex | celecoxib | Pfizer Inc. (originally Searle/Pharmacia) | marketed | Nonsteroidal Anti-inflammatory Drug [EPC] | COX-2 | 1998-12-31 |
| Cytotec | Misoprostol | Pfizer | marketed | NSAID combined with prostaglandin analog | Cyclooxygenase (COX-1 and COX-2); Prostaglandin receptors | 1988-01-01 |
| Celecoxib (Celebrex) | Celecoxib (Celebrex) | National Eye Institute (NEI) | marketed | Selective COX-2 inhibitor (coxib) | COX-2 (Cyclooxygenase-2) | |
| NSAI treatment | NSAI treatment | London School of Hygiene and Tropical Medicine | marketed | Nonsteroidal anti-inflammatory drug (NSAID) | Cyclooxygenase (COX-1 and/or COX-2) | |
| VIMOVO 500/20 | VIMOVO 500/20 | Amgen | marketed | NSAID with proton pump inhibitor combination | COX-1/COX-2 (naproxen); H+/K+-ATPase (esomeprazole) | |
| Metamizole and Ibuprofen | Metamizole and Ibuprofen | University Hospital, Basel, Switzerland | marketed | Nonsteroidal anti-inflammatory drug (NSAID) combination | Cyclooxygenase (COX-1 and COX-2) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
- — Celebrex · 10722456 · Formulation · US
- — Celebrex · 10799517 · Formulation · US
- — Celebrex · 9949990 · Formulation · US
- — Celebrex · 9795620 · Formulation · US
- — Celebrex · 9572819 · Formulation · US
- — Celebrex · 10376527 · Formulation · US
Sponsor landscape (NSAID class)
- Antibe Therapeutics Inc. · 3 drugs in this class
- Iroko Pharmaceuticals, LLC · 3 drugs in this class
- Organon and Co · 2 drugs in this class
- Apsen Farmaceutica S.A. · 2 drugs in this class
- Amneal Pharmaceuticals, LLC · 2 drugs in this class
- Behar, Caren, M.D. · 2 drugs in this class
- IDEA AG · 2 drugs in this class
- Noven Pharmaceuticals, Inc. · 2 drugs in this class
- HALEON · 2 drugs in this class
- Pfizer · 2 drugs in this class
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Cite this brief
Drug Landscape (2026). ATB-346 mid-dose — Competitive Intelligence Brief. https://druglandscape.com/ci/atb-346-mid-dose. Accessed 2026-06-10.
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