Who are aprotonin; epsilon aminocaproic acid's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Trasylol, Cyklokapron, Amicar, Tranexamic Acid Injectable Solution, Tranexamic Acid Dosage 1, Tranexamic Acid Irrigation.

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Last reviewed 2026-05-17 · How we verify

aprotonin; epsilon aminocaproic acid — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

aprotonin; epsilon aminocaproic acid (aprotonin; epsilon aminocaproic acid) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Antifibrinolytic agent. Area: Cardiovascular / Surgery.

marketed Antifibrinolytic agent Plasmin, kallikrein, plasminogen activators Cardiovascular / Surgery Small molecule Live · refreshed every 30 min

Target snapshot

aprotonin; epsilon aminocaproic acid (aprotonin; epsilon aminocaproic acid) — University of Rochester. This combination inhibits fibrinolysis by blocking plasmin-mediated clot breakdown, thereby reducing bleeding during and after surgery.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
aprotonin; epsilon aminocaproic acid TARGET	aprotonin; epsilon aminocaproic acid	University of Rochester	marketed	Antifibrinolytic agent	Plasmin, kallikrein, plasminogen activators
Trasylol	APROTININ	Bayer	marketed	Antifibrinolytic Agent	Plasminogen	1993-01-01
Cyklokapron	TRANEXAMIC ACID	Exela Pharma	marketed	Antifibrinolytic Agent [EPC]	Plasminogen	1986-01-01
Amicar	AMINOCAPROIC ACID	Epic Pharma Llc	marketed	Antifibrinolytic Agent [EPC]	Plasminogen	1964-01-01
Tranexamic Acid Injectable Solution	Tranexamic Acid Injectable Solution	Mount Sinai Hospital, Canada	marketed	Antifibrinolytic agent	Plasminogen / Plasmin
Tranexamic Acid Dosage 1	Tranexamic Acid Dosage 1	Chinese Academy of Medical Sciences, Fuwai Hospital	marketed	Antifibrinolytic agent	Plasminogen / Plasmin
Tranexamic Acid Irrigation	Tranexamic Acid Irrigation	University of Wisconsin, Madison	marketed	Antifibrinolytic agent	Plasminogen / Plasmin

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Antifibrinolytic agent class)

Montefiore Medical Center · 2 drugs in this class
Pfizer · 2 drugs in this class
Hamilton Health Sciences Corporation · 2 drugs in this class
Chinese Academy of Medical Sciences, Fuwai Hospital · 1 drug in this class
Henry Ford Health System · 1 drug in this class
Massachusetts General Hospital · 1 drug in this class
NYU Langone Health · 1 drug in this class
Mount Sinai Hospital, Canada · 1 drug in this class
Dr. Lutfi Kirdar Kartal Training and Research Hospital · 1 drug in this class
Carlos A Acosta-Olivo · 1 drug in this class

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Cite this brief

Drug Landscape (2026). aprotonin; epsilon aminocaproic acid — Competitive Intelligence Brief. https://druglandscape.com/ci/aprotonin-epsilon-aminocaproic-acid. Accessed 2026-05-17.

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