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Aprepitant+palonosetron+dexamethasone — Competitive Intelligence Brief

Aprepitant+palonosetron+dexamethasone (Aprepitant+palonosetron+dexamethasone) competitive landscape: 0 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Antiemetic combination (NK1 antagonist + 5-HT3 antagonist + corticosteroid). Area: Oncology.

phase 3 Antiemetic combination (NK1 antagonist + 5-HT3 antagonist + corticosteroid) NK1 receptor, 5-HT3 receptor, glucocorticoid receptor Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Aprepitant+palonosetron+dexamethasone (Aprepitant+palonosetron+dexamethasone) — Union Hospital, Tongji Medical College, Huazhong University of Science and Technology. This combination blocks chemotherapy-induced nausea and vomiting (CINV) through three complementary pathways: NK1 receptor antagonism, 5-HT3 receptor antagonism, and glucocorticoid anti-inflammatory effects.

Comparator set

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Aprepitant+palonosetron+dexamethasone TARGET Aprepitant+palonosetron+dexamethasone Union Hospital, Tongji Medical College, Huazhong University of Science and Technology phase 3 Antiemetic combination (NK1 antagonist + 5-HT3 antagonist + corticosteroid) NK1 receptor, 5-HT3 receptor, glucocorticoid receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Antiemetic combination (NK1 antagonist + 5-HT3 antagonist + corticosteroid) class)

  1. Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Aprepitant+palonosetron+dexamethasone — Competitive Intelligence Brief. https://druglandscape.com/ci/aprepitant-palonosetron-dexamethasone. Accessed 2026-05-17.

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