Who are Any treatment for cluster headache's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): ZAVEGEPANT, rimegepant 75 mg ODT, Placebo-Matching Atogepant, CGRP mAbs and onabotulinumtoxin A, Placebo to telcagepant tablets, Placebo to Telcagepant.

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Last reviewed 2026-05-17 · How we verify

Any treatment for cluster headache — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Any treatment for cluster headache (Any treatment for cluster headache) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: CGRP receptor antagonist. Area: Neurology.

phase 2 CGRP receptor antagonist CGRP receptor Neurology Small molecule Live · refreshed every 30 min

Target snapshot

Any treatment for cluster headache (Any treatment for cluster headache) — Samsung Medical Center. This drug targets the calcitonin gene-related peptide (CGRP) receptor to prevent cluster headache attacks.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Any treatment for cluster headache TARGET	Any treatment for cluster headache	Samsung Medical Center	phase 2	CGRP receptor antagonist	CGRP receptor
ZAVEGEPANT	ZAVEGEPANT		marketed		CGRP receptor	2023-01-01
rimegepant 75 mg ODT	rimegepant-75-mg-odt	Pfizer	marketed	CGRP receptor antagonist	CGRP receptors
Placebo-Matching Atogepant	Placebo-Matching Atogepant	AbbVie	phase 3	CGRP receptor antagonist	CGRP receptor (calcitonin gene-related peptide receptor)
CGRP mAbs and onabotulinumtoxin A	CGRP mAbs and onabotulinumtoxin A	Oslo University Hospital	phase 3	Monoclonal antibody + neurotoxin combination	CGRP/CGRP receptor and acetylcholine (via SNARE complex inhibition)
Placebo to telcagepant tablets	Placebo to telcagepant tablets	Merck Sharp & Dohme LLC	phase 3	CGRP receptor antagonist	CGRP receptor
Placebo to Telcagepant	Placebo to Telcagepant	Merck Sharp & Dohme LLC	phase 3	CGRP receptor antagonist	CGRP receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (CGRP receptor antagonist class)

Merck Sharp & Dohme LLC · 3 drugs in this class
Pfizer · 3 drugs in this class
Biohaven Therapeutics Ltd. · 2 drugs in this class
AbbVie · 1 drug in this class
Samsung Medical Center · 1 drug in this class
Pfizer Inc. · 1 drug in this class
Amgen · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Any treatment for cluster headache — Competitive Intelligence Brief. https://druglandscape.com/ci/any-treatment-for-cluster-headache. Accessed 2026-05-17.

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