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Antithymocyte globulin — Competitive Intelligence Brief
marketed
Polyclonal antithymocyte antibody
Multiple T-cell surface antigens (CD2, CD3, CD4, CD8, HLA-DR)
Immunology
Small molecule
Live · refreshed every 30 min
Target snapshot
Antithymocyte globulin (Antithymocyte globulin) — National Institute of Allergy and Infectious Diseases (NIAID). Antithymocyte globulin (ATG) is a polyclonal antibody preparation that depletes T lymphocytes by binding to and eliminating T cells in the circulation and lymphoid tissues.
Comparator set (4 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Antithymocyte globulin TARGET | Antithymocyte globulin | National Institute of Allergy and Infectious Diseases (NIAID) | marketed | Polyclonal antithymocyte antibody | Multiple T-cell surface antigens (CD2, CD3, CD4, CD8, HLA-DR) | |
| tacrolimus, ATG | tacrolimus, ATG | University Hospital, Toulouse | marketed | Calcineurin inhibitor and polyclonal antithymocyte antibody | Calcineurin (tacrolimus); T-cell surface antigens including CD2, CD3, CD4, CD8, CD25 (ATG) | |
| ATG | ATG | ITB-Med LLC | marketed | Polyclonal antithymocyte antibody | T-cell surface antigens (CD2, CD3, CD4, CD8, and other T-cell markers) | |
| Anti-Thymocyte Globulins treatment | Anti-Thymocyte Globulins treatment | Nantes University Hospital | marketed | Polyclonal antithymocyte antibody | T-cell surface antigens (CD2, CD3, CD4, CD8, HLA-DR) | |
| rabbit anti-thymocyte globulin - 4 doses | rabbit anti-thymocyte globulin - 4 doses | University of Nebraska | marketed | Polyclonal antithymocyte antibody | T lymphocyte surface antigens (CD2, CD3, CD4, CD8, HLA-DR) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Polyclonal antithymocyte antibody class)
- ITB-Med LLC · 1 drug in this class
- Nantes University Hospital · 1 drug in this class
- National Institute of Allergy and Infectious Diseases (NIAID) · 1 drug in this class
- University of Nebraska · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Antithymocyte globulin — Competitive Intelligence Brief. https://druglandscape.com/ci/antithymocyte-globulin. Accessed 2026-06-09.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing