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anti-CD 25 mAb, Sirolimus, MMF — Competitive Intelligence Brief
phase 3
Monoclonal antibody
CD25
Immunology
Small molecule
Live · refreshed every 30 min
Target snapshot
anti-CD 25 mAb, Sirolimus, MMF (anti-CD 25 mAb, Sirolimus, MMF) — University of Regensburg. Anti-CD 25 mAb targets and binds to the CD25 receptor on T cells, preventing their activation and proliferation.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| anti-CD 25 mAb, Sirolimus, MMF TARGET | anti-CD 25 mAb, Sirolimus, MMF | University of Regensburg | phase 3 | Monoclonal antibody | CD25 | |
| anti-CD25 rhMAb | anti-CD25 rhMAb | Peking University People's Hospital | marketed | CD25 antagonist monoclonal antibody | CD25 (IL-2 receptor alpha chain) | |
| Thymoglobulin (ATG) | Thymoglobulin (ATG) | M.D. Anderson Cancer Center | marketed | Polyclonal antithymocyte globulin (ATG) | Multiple T-cell antigens (CD2, CD3, CD4, CD8, CD11a, CD18, CD25, HLA-DR) | |
| Thymoglobuline Genzyme | Thymoglobuline Genzyme | University Hospital, Basel, Switzerland | marketed | Polyclonal antithymocyte globulin (ATG) | Multiple T-cell surface antigens (CD2, CD3, CD4, CD8, CD11a, CD18, CD25, HLA-DR, and others) | |
| Basiliximab treatment | Basiliximab treatment | Nantes University Hospital | marketed | Monoclonal antibody; IL-2 receptor antagonist | CD25 (IL-2 receptor alpha chain) | |
| tacrolimus, ATG | tacrolimus, ATG | University Hospital, Toulouse | marketed | Calcineurin inhibitor and polyclonal antithymocyte antibody | Calcineurin (tacrolimus); T-cell surface antigens including CD2, CD3, CD4, CD8, CD25 (ATG) | |
| Individual ATG | Individual ATG | The First Affiliated Hospital of Soochow University | marketed | Polyclonal antithymocyte globulin (immunosuppressant) | T lymphocytes (CD2, CD3, CD4, CD8, CD25 antigens) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Monoclonal antibody class)
- Pfizer · 7 drugs in this class
- argenx · 7 drugs in this class
- Johnson & Johnson · 2 drugs in this class
- German CLL Study Group · 2 drugs in this class
- Amgen · 2 drugs in this class
- Hoffmann-La Roche · 2 drugs in this class
- Brii Biosciences Limited · 2 drugs in this class
- Alexion Pharmaceuticals, Inc. · 2 drugs in this class
- Biotest · 2 drugs in this class
- Fondazione Italiana Linfomi - ETS · 2 drugs in this class
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Cite this brief
Drug Landscape (2026). anti-CD 25 mAb, Sirolimus, MMF — Competitive Intelligence Brief. https://druglandscape.com/ci/anti-cd-25-mab-sirolimus-mmf. Accessed 2026-05-16.
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