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Antagon ™ — Competitive Intelligence Brief
marketed
GnRH antagonist
GnRH receptor
Reproductive Medicine / Fertility
Small molecule
Live · refreshed every 30 min
Target snapshot
Antagon ™ (Antagon ™) — EMD Serono. Antagon is a gonadotropin-releasing hormone (GnRH) antagonist that rapidly suppresses luteinizing hormone (LH) and follicle-stimulating hormone (FSH) to prevent premature ovulation during assisted reproductive technology.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Antagon ™ TARGET | Antagon ™ | EMD Serono | marketed | GnRH antagonist | GnRH receptor | |
| Lupron | leuprorelin | Accord Healthcare S.L.U. | marketed | Gonadotropin Releasing Hormone Receptor Agonist | GnRH receptors | 1985-01-01 |
| Micronor | norethisterone | Johnson & Johnson | marketed | Progestin | GnRH receptors | 1962-01-01 |
| Gonapeptyl® | Gonapeptyl® | University Hospital, Ghent | marketed | GnRH agonist | GnRH receptor | |
| LhRH-antagonist | LhRH-antagonist | Turku University Hospital | marketed | GnRH/LhRH antagonist | GnRH receptor (LhRH receptor) | |
| Ultra-Long GnRH Agonists + Letrozole | Ultra-Long GnRH Agonists + Letrozole | University of Palermo | marketed | GnRH agonist + aromatase inhibitor combination | GnRH receptor; aromatase (CYP19A1) | |
| Cetrorelix and Leuprolide | Cetrorelix and Leuprolide | Instituto Valenciano de Infertilidad, IVI VALENCIA | marketed | GnRH antagonist and GnRH agonist combination | GnRH receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (GnRH antagonist class)
- Jiangsu HengRui Medicine Co., Ltd. · 2 drugs in this class
- Instituto Valenciano de Infertilidad, IVI VALENCIA · 2 drugs in this class
- AEterna Zentaris · 2 drugs in this class
- El Shatby University Hospital for Obstetrics and Gynecology · 1 drug in this class
- Eugonia · 1 drug in this class
- Instituto de Investigacion Sanitaria La Fe · 1 drug in this class
- Merck KGaA, Darmstadt, Germany · 1 drug in this class
- Rabin Medical Center · 1 drug in this class
- Sumitomo Pharma Switzerland GmbH · 1 drug in this class
- University of Edinburgh · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Antagon ™ — Competitive Intelligence Brief. https://druglandscape.com/ci/antagon. Accessed 2026-05-13.
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