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Amlodipine, losartan potassium and hydrochlorothiazide — Competitive Intelligence Brief
phase 3
Antihypertensive combination (calcium channel blocker + angiotensin II receptor blocker + thiazide diuretic)
L-type calcium channels, AT1 angiotensin II receptor, sodium-chloride cotransporter
Cardiovascular
Small molecule
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Target snapshot
Amlodipine, losartan potassium and hydrochlorothiazide (Amlodipine, losartan potassium and hydrochlorothiazide) — Shanghai WiseGain Medical Devices Co., Ltd.. This triple-combination antihypertensive reduces blood pressure through three complementary mechanisms: calcium channel blockade, angiotensin II receptor antagonism, and thiazide diuresis.
Comparator set (1 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Amlodipine, losartan potassium and hydrochlorothiazide TARGET | Amlodipine, losartan potassium and hydrochlorothiazide | Shanghai WiseGain Medical Devices Co., Ltd. | phase 3 | Antihypertensive combination (calcium channel blocker + angiotensin II receptor blocker + thiazide diuretic) | L-type calcium channels, AT1 angiotensin II receptor, sodium-chloride cotransporter | |
| Amlodipine/Losartan/Chlorthalidone | Amlodipine/Losartan/Chlorthalidone | Hanmi Pharmaceutical Company Limited | marketed | Antihypertensive combination (calcium channel blocker + angiotensin II receptor blocker + thiazide diuretic) | L-type calcium channels, AT1 angiotensin II receptor, sodium-chloride cotransporter |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antihypertensive combination (calcium channel blocker + angiotensin II receptor blocker + thiazide diuretic) class)
- Hanmi Pharmaceutical Company Limited · 1 drug in this class
- Shanghai WiseGain Medical Devices Co., Ltd. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Amlodipine, losartan potassium and hydrochlorothiazide — Competitive Intelligence Brief. https://druglandscape.com/ci/amlodipine-losartan-potassium-and-hydrochlorothiazide. Accessed 2026-05-18.
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