Who are Amlodipine + HCTZ's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Amlodipine plus Hydrochlorothiazide, Perindopril + amlodipine + if necessary, hydrochlorothiazide.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-16 · How we verify

Amlodipine + HCTZ — Competitive Intelligence Brief

Amlodipine + HCTZ (Amlodipine + HCTZ) competitive landscape: 2 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Calcium channel blocker + thiazide diuretic combination. Area: Cardiovascular.

phase 3 Calcium channel blocker + thiazide diuretic combination L-type voltage-gated calcium channel (amlodipine); sodium-chloride cotransporter (HCTZ) Cardiovascular Small molecule Live · refreshed every 30 min

Target snapshot

Amlodipine + HCTZ (Amlodipine + HCTZ) — Novartis. Amlodipine relaxes blood vessels by blocking calcium channels, while HCTZ reduces blood volume by increasing sodium and water excretion through the kidneys, together lowering blood pressure.

Comparator set (2 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Amlodipine + HCTZ TARGET	Amlodipine + HCTZ	Novartis	phase 3	Calcium channel blocker + thiazide diuretic combination	L-type voltage-gated calcium channel (amlodipine); sodium-chloride cotransporter (HCTZ)
Amlodipine plus Hydrochlorothiazide	Amlodipine plus Hydrochlorothiazide	University of Abuja	marketed	Calcium channel blocker + thiazide diuretic combination	L-type voltage-gated calcium channel (amlodipine); sodium-chloride cotransporter (hydrochlorothiazide)
Perindopril + amlodipine + if necessary, hydrochlorothiazide	Perindopril + amlodipine + if necessary, hydrochlorothiazide	Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company	marketed	ACE inhibitor + calcium channel blocker + thiazide diuretic combination	Angiotensin-converting enzyme (ACE), L-type calcium channels, sodium-chloride cotransporter

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Calcium channel blocker + thiazide diuretic combination class)

Novartis · 1 drug in this class
University of Abuja · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Amlodipine + HCTZ — Competitive Intelligence Brief. https://druglandscape.com/ci/amlodipine-hctz. Accessed 2026-05-16.

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