Who are aminolevulinic acid (ALA)'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Rose Bengal, Hemoporfin PDT, padeliporfin VTP, SGX301 (synthetic hypericin), 8-methoxypsoralen, verteporfin, bevacizumab, triamcinolone acetonide.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-16 · How we verify

aminolevulinic acid (ALA) — Competitive Intelligence Brief

aminolevulinic acid (ALA) (aminolevulinic acid (ALA)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Photosensitizer. Area: Oncology.

marketed Photosensitizer Protoporphyrin IX (endogenous photosensitizer generated from ALA) Oncology Small molecule Live · refreshed every 30 min

Target snapshot

aminolevulinic acid (ALA) (aminolevulinic acid (ALA)) — University of California, Davis. Aminolevulinic acid is a precursor to protoporphyrin IX, which accumulates in cells and generates reactive oxygen species when activated by light, enabling photodynamic therapy.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
aminolevulinic acid (ALA) TARGET	aminolevulinic acid (ALA)	University of California, Davis	marketed	Photosensitizer	Protoporphyrin IX (endogenous photosensitizer generated from ALA)
Rose Bengal	Rose Bengal	University of California, San Francisco	marketed	Photosensitizer
Hemoporfin PDT	Hemoporfin PDT	Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd.	marketed	Photosensitizer	Porphyrin-based photosensitizer (non-receptor mediated)
padeliporfin VTP	padeliporfin VTP	Steba Biotech S.A.	phase 3	Photosensitizer
SGX301 (synthetic hypericin)	SGX301 (synthetic hypericin)	Soligenix	phase 3	Photosensitizer	Hypericin (photosensitizing agent); generates ROS upon light activation
8-methoxypsoralen	8-methoxypsoralen	Medical University of Graz	phase 3	Psoralen photosensitizer	DNA (non-specific intercalating agent)
verteporfin, bevacizumab, triamcinolone acetonide	verteporfin, bevacizumab, triamcinolone acetonide	Shahid Beheshti University of Medical Sciences	phase 3	photosensitizer, monoclonal antibody, corticosteroid	VEGF-A, VEGF receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Photosensitizer class)

Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. · 2 drugs in this class
Soligenix · 1 drug in this class
Steba Biotech S.A. · 1 drug in this class
University of California, Davis · 1 drug in this class
University of California, San Francisco · 1 drug in this class

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Cite this brief

Drug Landscape (2026). aminolevulinic acid (ALA) — Competitive Intelligence Brief. https://druglandscape.com/ci/aminolevulinic-acid-ala. Accessed 2026-05-16.

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