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ALMOTRIPTAN MALATE — Competitive Intelligence Brief
marketed
Triptan
5-HT1B/1D receptors
Neuroscience
Small molecule
Live · refreshed every 30 min
Target snapshot
ALMOTRIPTAN MALATE (ALMOTRIPTAN MALATE). Almotriptan malate is a selective 5-HT1B/1D receptor agonist that binds with high affinity to these receptors, leading to vasoconstriction and inhibition of neurogenic inflammation.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| ALMOTRIPTAN MALATE TARGET | ALMOTRIPTAN MALATE | marketed | Triptan | 5-HT1B/1D receptors | 2001-01-01 | |
| Sumatriptan and Naproxen sodium | Sumatriptan and Naproxen sodium | POZEN | marketed | Triptan/NSAID combination | 5-HT1B/1D receptors (sumatriptan); COX-1/COX-2 (naproxen sodium) | |
| Triptans | triptans | Pfizer | marketed | Selective serotonin receptor agonists | Serotonin 5-HT1B/1D receptors | |
| almotriptan or pseudoephedrine | almotriptan or pseudoephedrine | Clinvest | marketed | Triptan + sympathomimetic decongestant combination | 5-HT1B/1D receptors (almotriptan); alpha-adrenergic receptors (pseudoephedrine) | |
| conventional migraine drug treatment | conventional migraine drug treatment | Birjand University of Medical Sciences | marketed | Triptan, ergot alkaloid, or NSAID (class varies by specific agent) | 5-HT1B/1D receptors (triptans); COX inhibition (NSAIDs); or alpha-adrenergic/serotonergic receptors (ergots) | |
| Imitrex® | Imitrex® | Teva Pharmaceuticals USA | marketed | Triptan (5-HT1B/1D receptor agonist) | 5-HT1B and 5-HT1D receptors | |
| naratriptan HCl | naratriptan HCl | Cady, Roger, M.D. | marketed | Triptan (5-HT1B/1D receptor agonist) | 5-HT1B receptor, 5-HT1D receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Triptan class)
- · 1 drug in this class
- Assistance Publique Hopitaux De Marseille · 1 drug in this class
- HCA Florida North Florida Hospital · 1 drug in this class
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Cite this brief
Drug Landscape (2026). ALMOTRIPTAN MALATE — Competitive Intelligence Brief. https://druglandscape.com/ci/almotriptan-malate. Accessed 2026-05-14.
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