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Axert — Competitive Intelligence Brief
marketed
Serotonin-1b and Serotonin-1d Receptor Agonist
5-hydroxytryptamine receptor 1B
Neuroscience
Small molecule
Live · refreshed every 30 min
Target snapshot
Axert (ALMOTRIPTAN) — Johnson & Johnson. Axert works by binding to serotonin receptors in the brain to relieve migraine pain.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Axert TARGET | ALMOTRIPTAN | Johnson & Johnson | marketed | Serotonin-1b and Serotonin-1d Receptor Agonist | 5-hydroxytryptamine receptor 1B | 2001-01-01 |
| Relpax | ELETRIPTAN | Upjohn | marketed | Serotonin-1b and Serotonin-1d Receptor Agonist | 5-hydroxytryptamine receptor 1D | 2002-01-01 |
| Frova | FROVATRIPTAN | Endo Operations | marketed | Serotonin-1b and Serotonin-1d Receptor Agonist | 5-hydroxytryptamine receptor 1D | 2001-01-01 |
| Amerge | NARATRIPTAN | GSK | marketed | Serotonin-1b and Serotonin-1d Receptor Agonist | 5-HT 1B/1D receptors | 1998-01-01 |
| Maxalt | RIZATRIPTAN | Gensco | marketed | Serotonin-1b and Serotonin-1d Receptor Agonist | 5-hydroxytryptamine receptor 1D | 1998-01-01 |
| Zomig | ZOLMITRIPTAN | AstraZeneca | marketed | Serotonin-1b and Serotonin-1d Receptor Agonist [EPC] | 5-hydroxytryptamine receptor 1D | 1997-01-01 |
| Imitrex | SUMATRIPTAN | GSK | marketed | Serotonin-1b and Serotonin-1d Receptor Agonist | 5-hydroxytryptamine receptor 1D | 1992-01-01 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
- — Imitrex · 9974770 · Formulation · US
- — Imitrex · 11337962 · Formulation · US
- — Imitrex · 10603305 · Formulation · US
- — Imitrex · 9610280 · Formulation · US
- — Imitrex · 12090139 · Formulation · US
- — Imitrex · 9211282 · Formulation · US
Sponsor landscape (Serotonin-1b and Serotonin-1d Receptor Agonist class)
- GSK · 2 drugs in this class
- Endo Operations · 1 drug in this class
- Gensco · 1 drug in this class
- Johnson & Johnson · 1 drug in this class
- Upjohn · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Axert — Competitive Intelligence Brief. https://druglandscape.com/ci/almotriptan. Accessed 2026-05-14.
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