Who are Aliskiren/HCTZ's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Aliskiren Hydrochlorothiazide, Aliskiren+HCTZ - Phase 2.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-16 · How we verify

Aliskiren/HCTZ — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Aliskiren/HCTZ (Aliskiren/HCTZ) competitive landscape: 2 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Direct renin inhibitor / thiazide diuretic combination. Area: Cardiovascular.

phase 3 Direct renin inhibitor / thiazide diuretic combination Renin; sodium-chloride cotransporter Cardiovascular Small molecule Live · refreshed every 30 min

Target snapshot

Aliskiren/HCTZ (Aliskiren/HCTZ) — Novartis. Aliskiren/HCTZ is a fixed-dose combination that lowers blood pressure by blocking the renin-angiotensin system and promoting sodium and water excretion.

Comparator set (2 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Aliskiren/HCTZ TARGET	Aliskiren/HCTZ	Novartis	phase 3	Direct renin inhibitor / thiazide diuretic combination	Renin; sodium-chloride cotransporter
Aliskiren Hydrochlorothiazide	Aliskiren Hydrochlorothiazide	Novartis	marketed	Direct renin inhibitor / thiazide diuretic combination	Renin; sodium-chloride cotransporter (NCCT)
Aliskiren+HCTZ - Phase 2	Aliskiren+HCTZ - Phase 2	Novartis	phase 3	Direct renin inhibitor + thiazide diuretic combination	Renin; sodium-chloride cotransporter

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Direct renin inhibitor / thiazide diuretic combination class)

Novartis · 2 drugs in this class

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Cite this brief

Drug Landscape (2026). Aliskiren/HCTZ — Competitive Intelligence Brief. https://druglandscape.com/ci/aliskiren-hctz. Accessed 2026-05-16.

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