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AGN-241751 — Competitive Intelligence Brief
phase 2
Sodium-activated potassium channel inhibitor
Nav1.5
Cardiovascular
Small molecule
Live · refreshed every 30 min
Target snapshot
AGN-241751 (AGN-241751) — Syndeio Biosciences, Inc. AGN-241751 is a small molecule inhibitor of the sodium-activated potassium channel, Nav1.5.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| AGN-241751 TARGET | AGN-241751 | Syndeio Biosciences, Inc | phase 2 | Sodium-activated potassium channel inhibitor | Nav1.5 | |
| Medium-dose anrikefon | Medium-dose anrikefon | Peking University First Hospital | marketed | Sodium channel blocker | Nav1.5 | |
| Flecainide controlled release | Flecainide controlled release | MEDA Pharma GmbH & Co. KG | marketed | Class IC antiarrhythmic agent | Cardiac voltage-gated sodium channel (Nav1.5) | |
| Propafenone i.v. | Propafenone i.v. | Charles University, Czech Republic | marketed | Class IC antiarrhythmic agent | Cardiac sodium channel (Nav1.5) | |
| TAK-816 | TAK-816 | Takeda | phase 3 | Sodium-activated potassium channel inhibitor | Nav1.5 | |
| Group VTI | Group VTI | Kasr El Aini Hospital | phase 3 | sodium-activated potassium channel inhibitor | Nav1.5 | |
| Flecainide Injectable Solution | Flecainide Injectable Solution | Hippocration General Hospital | phase 3 | Class IC antiarrhythmic agent | Cardiac voltage-gated sodium channel (Nav1.5) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Sodium-activated potassium channel inhibitor class)
- Chiesi Farmaceutici S.p.A. · 1 drug in this class
- Chong Kun Dang Pharmaceutical · 1 drug in this class
- Jiangsu HengRui Medicine Co., Ltd. · 1 drug in this class
- Mylan Inc. · 1 drug in this class
- Pfizer · 1 drug in this class
- Syndeio Biosciences, Inc · 1 drug in this class
- Takeda · 1 drug in this class
- Teva Branded Pharmaceutical Products R&D, Inc. · 1 drug in this class
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- AGN-241751 CI watch — RSS
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- AGN-241751 CI watch — JSON
- AGN-241751 alone — RSS
- Whole Sodium-activated potassium channel inhibitor class — RSS
Cite this brief
Drug Landscape (2026). AGN-241751 — Competitive Intelligence Brief. https://druglandscape.com/ci/agn-241751. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing